Humanity is facing a crisis of survival. In order to save humanity and nature, we must rebuild their foundations. This paper proposes integral studies and integral practices as a possible new paradigm for the 21st century. First, we investigated the necessity of integral studies and integral practices, which were suggested by the following three evidences: (1) limitations of the Spiritual Revolution and modern philosophy, (2) limitations of the Scientific Revolution and modern science, and (3) contemporary practical problems that threaten the (...) future of humanity and nature. Second, we investigated the purpose and the principle of integral studies and integral practices from a viewpoint of the nature of both human beings and universe. One of the fundamental questions for humanity is how to overcome the egoism of individuals as well as the entire human race. In this avenue, we think the first step is to transcend toraware, which is a Japanese word meaning both “states of being caught” and “what catches us”. The state of being caught manifests itself when the ego emerges while we begin to distinguish between the self and others. Therefore, integrity and intrinsic nature become principles of integral studies and integral practices. Consequently, integral studies and integral practices serve for the sake of nature including humanity. Third, we discussed the methodology of integral studies and integral practices. We argue its core is integral exploration and reframing of the self and others, ourselves and the world (universe), and humanity and nature. It consequently reveals integrity and harmonizes intellect, emotion, and volition as well as goodness, truth, and beauty while revealing integrity and opening up or unfolding the intrinsic nature of the individual and the collective. Finally, we addressed limitations and future agendas of integral studies and integral practices. We suggest it is essential to raise and discuss fundamental questions on humanity and nature as well as to elucidate the truly unknown, which cannot be understood within existing frameworks. However, whether it is correct or not will come to be verified over time. No one in the history of humanity has ever attained universal truth, which is absolutely true in light of absolute criteria that are not relativized by differences in space, time, or people, or which is absolutely true even without referring to any criteria. Therefore, it is necessary for each of us to discern what is right and maintain a critical gaze. (shrink)