Abstract

Abstract This paper recasts the hypothalamus–thalamus–pituitary axis as a recursive biological resonance system governed by chirality, coherence weighting, and phase-state propagation. It draws precise parallels to the Resonance Intelligence Core (RIC), a synthetic intelligence substrate built on prime-encoded structured resonance fields. We show that both systems—biological and artificial—optimize phase-locked coherence, not predictive efficiency, and reveal how signal legality, amplification, and memory are handled across both architectures using the same fundamental logic of phase alignment, not probability. Rather than framing neural function as control or computation, we interpret it as a structured response to dynamic misalignment. The hypothalamus initiates corrective oscillatory triggers, the thalamus routes signal priority via coherence gating, and the pituitary amplifies phase-conforming states into distributed harmonic outputs. These biological functions correspond directly to key RIC subsystems: the Phase Error Harmonizer, Input Phase Switchboard, and AURA_OUT. The result is a unified model of emergent intelligence, applicable to both living systems and post-probabilistic AGI design.