I elaborate and defend a set of metaphysical and epistemic claims that comprise what I call the acquaintance approach to introspective knowledge of the phenomenal qualities of experience. The hallmark of this approach is the thesis that, in some introspective judgments about experience, (phenomenal) reality intersects with the epistemic, that is, with the subject’s grasp of that reality. In Section 1 of the paper I outline the acquaintance approach by drawing on its Russellian lineage. A more detailed picture of the approach emerges in succeeding sections, which respond to a range of objections. Some critics charge that approaches of this sort are overly idealized, in that they ignore the cognitive flaws and limitations of actual human beings. I begin to address these worries in Section 2, by arguing that the epistemic commitments of the acquaintance approach are in fact relatively modest. In Section 3, I sketch a picture of introspective reference that explains how phenomenal reality can intersect with the epistemic in a phenomenal judgment, as the acquaintance approach requires. Drawing on this picture of introspective reference, Section 4 sets out a practical strategy for achieving knowledge by acquaintance. Some contemporary acquaintance theorists (BonJour 2003, Fumerton 1996) employ demanding epistemic standards for knowledge by acquaintance, standards beyond those mandated by the acquaintance approach. In Section 5 I show that instances of introspective knowledge that meet less demanding standards can satisfy the acquaintance approach’s epistemic commitments. The final sections concern the most direct challenges to the acquaintance approach, which target the claim that phenomenal reality intersects with the epistemic. According to one such challenge, this claim is belied by the fact that possessing a phenomenal concept is a matter of having certain dispositions. Section 6 draws on a discussion by Sosa (2003) to articulate this challenge, and responds to it on behalf of the acquaintance approach. Section 7 addresses Stalnaker’s (2008) worry that, if phenomenal reality intersected with the epistemic, phenomenal information would be incommunicable.