Chimeras intended for human gamete production: an ethical alternative?

Reproductive Biomedicine Online 35 (4):387-390 (2017)
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Human eggs for basic, fertility and stem-cell research are in short supply. Many experiments that require their use cannot be carried out at present, and, therefore, the benefits that could emerge from these are either delayed or never materialise. This state of affairs is problematic for scientists and patients worldwide, and it is a matter that needs our attention. Recent advances in chimera research have opened the possibility of creating human/non-human animal chimeras intended for human gamete production (chimeras-IHGP). In this paper, I examine four arguments against the creation of such chimeras and prove that all of them are found wanting. I conclude by showing that there is a strong moral reason for scientists to pursue this research avenue.
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Necessary Conditions for Morally Responsible Animal Research.David Degrazia & Jeff Sebo - 2015 - Cambridge Quarterly of Healthcare Ethics 24 (4):420-430.

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