GABAA Receptor Deficits Predict Recovery in Patients With Disorders of Consciousness: A Preliminary Multimodal [11C]Flumazenil PET and fMRI Study

Human Brain Mapping:DOI: 10.1002/hbm.22883 (2015)
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Abstract

Disorders of consciousness (DoC)—that is, unresponsive wakefulness syndrome/vegetative state and minimally conscious state—are debilitating conditions for which no reliable markers of consciousness recovery have yet been identified. Evidence points to the GABAergic system being altered in DoC, making it a potential target as such a marker.

Author Profiles

Georg Northoff
University of Ottawa
Timothy Joseph Lane
Academia Sinica

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