Abstract
In light of the pervasive developments of new technologies, such as NBIC (Nanotechnology, biotechnology, information technology, and cognitive science), it is imperative to produce a coherent and deep reflexion on the human nature, on human intelligence and on the limit of both of them, in order to successfully respond to some technical argumentations that strive to depict humanity as a purely mechanical system. For this purpose, it is interesting to refer to the epistemology and metaphysics of Thomas Aquinas as a stable philosophical reference on Human Nature. Indeed, we find in the works of Aquinas some of the most productive elements that could form a base to our deeper understanding of, and possibly even solutions to some of the most perplexing questions raised in our times by the existence of AI.