A prominent historiographic theme in the past decade has been a movement away from causal explanation of large-scale processes and outcomes and toward narrative interpretation of singular historical processes. This article argues for the continued vitality of large-scale historical inquiry and surveys the historiographic issues that arise in large-scale historical explanation. The article proceeds through an examination of several important recent examples of large-scale history: comparative history of Europe and China, the history of alternative forms of industrial organization, and the (...) history of technology. These three cases provide the basis for a conception of what may be called "conjunctural contingent meso-level" explanations: explanations that identify intermediate-level structures and processes and highlight both the structural factors that govern change and the multiple pathways that change can take. (shrink)