Abstract The Duhem?Quine thesis is generally presented as the radical underdetermi? nation of a theory by experimental evidence. But there is a much?neglected second aspect, i.e. the coherence or interrelatedness of the conceptual components of a theory. Although both Duhem and Quine recognised this aspect, they failed to see its consequences: it militates against the idea of radical underdetermination. Because scientific theories are coherent conceptual systems, empirical evidence penetrates, as it were, the periphery and allows the localisation of central, not (...) just peripheral hypotheses. There is then no reason to deny the existence of crucial experiments. Both these ideas are denied in the Quine?Duhem thesis. A discussion of the famous Stem?Gerlach experiment and the role of fundamental physical constants shows, however, that localisation is not only possible but essential for the validity of scientific theories. Quine's famous ?latitude of choice? turns out to be severely restricted. (shrink)

History and philosophy complement and overlap each other in subject matter, but the two disciplines exhibit conflict over methodology. Since Hempel's challenge to historians that they should adopt the covering law model of explanation, the methodological conflict has revolved around the respective roles of the general and the particular in each discipline. In recent years, the revival of narrativism in history, coupled with the trend in philosophy of science to rely upon case studies, joins the methodological conflict anew. So long (...) as contemporary philosophy of science relies upon history's methodology to construct its case studies, it subjects itself to a paradoxical situation: the better the history, the worse the philosophy. An example of the methodological conflict is presented in the case of Antoine Lavoisier. This example also serves our ultimateconclusion, which is that distinctively philosophical methods of case-study design promise enhanced prescriptive powers for philosophy of science. (shrink)