Switch to: Citations

Add references

You must login to add references.
  1. The somatic mutation theory of cancer: growing problems with the paradigm?Ana M. Soto & Carlos Sonnenschein - 2004 - Bioessays 26 (10):1097-1107.
    The somatic mutation theory has been the prevailing paradigm in cancer research for the last 50 years. Its premises are: (1) cancer is derived from a single somatic cell that has accumulated multiple DNA mutations, (2) the default state of cell proliferation in metazoa is quiescence, and (3) cancer is a disease of cell proliferation caused by mutations in genes that control proliferation and the cell cycle. From this compelling simplicity, an increasingly complicated picture has emerged as more than 100 (...)
    Download  
     
    Export citation  
     
    Bookmark   26 citations