Demands for public participation in technical decision-making are currently high on the agenda of Science & Technology Studies. It is assumed that the democratisation of technical decision-making processes generally leads to more socially desirable and acceptable outcomes. While this may be true in certain cases, this assumption cannot be generalised. I will discuss the case of the so-called ‘South African AZT debate’. The controversy started when President Thabo Mbeki, after reading some scientific papers on the toxicity of AZT, decided to (...) bar the use of the drug in the public health sector as a means to reduce the transmission of HIV from mothers to children. While the scientific mainstream accepts the effectiveness of AZT in reducing the risk of vertical HIV transmission, a few maverick scientists reject the clinical evidence and argue that the risks of using AZT by far outweigh its benefits. Based on various textual sources and using the ‘Periodic Table of Expertises’ developed by Collins and Evans, Mbeki’s expertise at the time of his intervention into the technical question whether AZT is a medicine or a poison can be classified as primary source knowledge. It is shown that this type of expertise is insufficient for technical decision-making. Mbeki’s primary source knowledge legitimated his presentation of the claims of maverick scientists as a serious contribution to the debate—with tragic consequences for tens of thousands of babies.Keywords: Primary source knowledge; Expertise; Technical decision-making; South Africa; AZT; AIDS. (shrink)

Programming languages are, at the same time, instruments and communicative artifacts that evolve rapidly through use. In this paper I describe an online computing platform called BioBike. BioBike is a trading zone where biologists and programmers collaborate in the development of an extended vocabulary and functionality for computational genomics. In the course of this work they develop interactional expertise with one another’s domains. The extended BioBike vocabulary operates on two planes: as a working programming language, and as a pidgin in (...) the conversation between the biologists and engineers. The flexibility that permits this community to dynamically extend BioBike’s working vocabulary—to form new pidgins—makes BioBike unique among computational tools, which usually are not themselves adapted through the collaborations that they facilitate. Thus BioBike is itself a crucial feature—which it is tempting to refer to as a participant—in the developing interaction.Keywords: Trading zones; Collaboration; Interactional expertise; Genomics; Computer programming languages; Lisp. (shrink)

In this paper we explore the practice of interdisciplinarity by examining how the UK research councils addressed the problem of the sustainable city during the 1990s. In developing their research programmes, the councils recognised that the problems of the sustainable city transcended conventional disciplinary boundaries and that an interdisciplinary approach was needed. In practice, however, initially radical proposals to research the city as a complex combination of science and technology and society contracted into more cognate collaborations that emphasised either science (...) or technology or society, with the result that interdisciplinarity came to be located within research councils rather than between them. This, in turn, led to the development of a third kind of interdisciplinarity as the responsibility for making the connections between the research programmes was outsourced to the user communities—the local authorities. Unfortunately, local authorities struggled to find the resources to conduct this work so that the radical interdisciplinarity recommended at the start of the decade remained unaccomplished at the end. In describing these events we emphasise roles of paradigms and epistemic cultures in shaping research approaches and the complications they raise for the triangulation between approaches that is assumed in the idea of interdisciplinarity. We do not wish to be entirely negative, however, and conclude by suggesting some ways in which the quality and success of this much-needed interdisciplinary work could be increased. (shrink)