In this important new work, Haack develops an original theory of empirical evidence or justification, and argues its appropriateness to the goals of inquiry. In so doing, Haack provides detailed critical case studies of Lewis's foundationalism; Davidson's and Bonjour's coherentism; Popper's 'epistemology without a knowing subject'; Quine's naturalism; Goldman's reliabilism; and Rorty's, Stich's, and the Churchlands' recent obituaries of epistemology.

After a 50-page outline of the principles of clinical reasoning, over 60 actual cases are detailed that illustrate (and are keyed to) the principles, presenting case records, analysis, and references to literature. For medical students and interns, and their instructors. Annotation copyright Book Ne.

An enormous intellectual adventure. In this groundbreaking new book, the American biologist Edward O. Wilson, considered to be one of the world's greatest living scientists, argues for the fundamental unity of all knowledge and the need to search for consilience --the proof that everything in our world is organized in terms of a small number of fundamental natural laws that comprise the principles underlying every branch of learning. Professor Wilson, the pioneer of sociobiology and biodiversity, now once again breaks out (...) of the conventions of current thinking. He shows how and why our explosive rise in intellectual mastery of the truths of our universe has its roots in the ancient Greek concept of an intrinsic orderliness that governs our cosmos and the human species--a vision that found its apogee in the Age of Enlightenment, then gradually was lost in the increasing fragmentation and specialization of knowledge in the last two centuries. Drawing on the physical sciences and biology, anthropology, psychology, religion, philosophy, and the arts, Professor Wilson shows why the goals of the original Enlightenment are surging back to life, why they are reappearing on the very frontiers of science and humanistic scholarship, and how they are beginning to sketch themselves as the blueprint of our world as it most profoundly, elegantly, and excitingly is. (shrink)

The proposed practice of "evidence-based medicine," which calls for careful clinical judgment in evaluating the "best available evidence," should be differentiated from the special collection of data regarded as suitable evidence. Although the proposed practice does not seem new, the new collection of "best available" information has major constraints for the care of individual patients. Derived almost exclusively from randomized trials and meta-analyses, the data do not include many types of treatments or patients seen in clinical practice; and the results (...) show comparative efficacy of treatment for an "average" randomized patient, not for pertinent subgroups formed by such cogent clinical features as severity of symptoms, illness, co-morbidity, and other clinical nuances. The intention-to-treat analyses do not reflect important post-randomization events leading to altered treatment; and the results seldom provide suitable background data when therapy is given prophylactically rather than remedially, or when therapeutic advantages are equivocal. Randomized trial information is also seldom available for issues in etiology, diagnosis, and prognosis, and for clinical decisions that depend on pathophysiologic changes, psychosocial factors and support, personal preferences of patients, and strategies for giving comfort and reassurance. The laudable goal of making clinical decisions based on evidence can be impaired by the restricted quality and scope of what is collected as "best available evidence." The authoritative aura given to the collection, however, may lead to major abuses that produce inappropriate guidelines or doctrinaire dogmas for clinical practice. (shrink)