The positivists suggest that some truths may be immune from empirical refutation and yet lacking in rational justification. Quine holds that every proposition is in principle empirically refutable so there are no a priori truths. I’ll provide a working characterization of the idea of “rational revisability” and argue it’s impossible for us to take a chain of rational revision and end up revising everything which we now believe. Quine's position on revisability is also in tension with certain theses about epistemic (...) holism. Finally, I discuss a more general context in which rational argument is viewed as one mechanism among many for reliably modifying beliefs. This more biological perspective allows us to formulate Quine's claims about revisability in a new way and to raise some interesting questions about the potential impact of natural selection on our cognitive capacities. (shrink)