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Consenting for current genetic research: is Canadian practice adequate?

Iris Jaitovich Groisman, Nathalie Egalite & Beatrice Godard

BMC Medical Ethics 15 (1):80 (2014)

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Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries.Nola M. Ries, Jane LeGrandeur & Timothy Caulfield - 2010 - BMC Medical Ethics 11 (1):4.details Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropriate protection of children and families as research participants. Long-term studies with a genetic component involve collection, retention and use of biological samples and personal information over many years. Cohort studies may be established to study specific conditions (e.g. autism, asthma) or may have a broad aim to research a range of (...) Download Export citation Bookmark 11 citations
(1 other version)Genetic Counseling.[author unknown] - 1979 - Ethics and Medics 4 (6):3-4.details Download Export citation Bookmark 11 citations
Use of next generation sequencing technologies in research and beyond: are participants with mental health disorders fully protected? [REVIEW]Groisman Iris Jaitovich, Mathieu Ghislaine & Godard Beatrice - 2012 - BMC Medical Ethics 13 (1):36-.details Background Next Generation Sequencing (NGS) is expected to help find the elusive, causative genetic defects associated with Bipolar Disorder (BD). This article identifies the importance of NGS and further analyses the social and ethical implications of this approach when used in research projects studying BD, as well as other psychiatric ailments, with a view to ensuring the protection of research participants. Methods We performed a systematic review of studies through PubMed, followed by a manual search through the titles and abstracts (...) Download Export citation Bookmark 1 citation
Ethical implications of the use of whole genome methods in medical research.Jane Kaye, Paula Boddington, Jantina de Vries, Naomi Hawkins & Karen Melham - unknowndetails The use of genome-wide association studies in medical research and the increased ability to share data give a new twist to some of the perennial ethical issues associated with genomic research. GWAS create particular challenges because they produce fine, detailed, genotype information at high resolution, and the results of more focused studies can potentially be used to determine genetic variation for a wide range of conditions and traits. The information from a GWA scan is derived from DNA that is a (...) Download Export citation Bookmark 10 citations

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