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Responsible risking, forethought, and the case of germline gene editing

In Adriana Placani & Stearns Broadhead (eds.), _Risk and Responsibility in Context_. New York: Routledge. pp. 149-169 (2023)

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  1. Our Posthuman Future: Consequences of the Biotechnology Revolution.Carl Elliott & Francis Fukuyama - 2002 - Hastings Center Report 32 (6):42.
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  • Bioethics and Transhumanism.Porter Allen - 2017 - Journal of Medicine and Philosophy 42 (3):237-260.
    Transhumanism is a “technoprogressive” socio-political and intellectual movement that advocates for the use of technology in order to transform the human organism radically, with the ultimate goal of becoming “posthuman.” To this end, transhumanists focus on and encourage the use of new and emerging technologies, such as genetic engineering and brain-machine interfaces. In support of their vision for humanity, and as a way of reassuring those “bioconservatives” who may balk at the radical nature of that vision, transhumanists claim common ground (...)
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  • (1 other version)Humanity's End: Why We Should Reject Radical Enhancement.Nicholas Agar - 2013 - Bradford.
    Proposals to make us smarter than the greatest geniuses or to add thousands of years to our life spans seem fit only for the spam folder or trash can. And yet this is what contemporary advocates of radical enhancement offer in all seriousness. They present a variety of technologies and therapies that will expand our capacities far beyond what is currently possible for human beings. In _Humanity's End,_ Nicholas Agar argues against radical enhancement, describing its destructive consequences. Agar examines the (...)
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  • Responsibility as Answerability.Angela M. Smith - 2015 - Inquiry: An Interdisciplinary Journal of Philosophy 58 (2):99-126.
    ABSTRACTIt has recently become fashionable among those who write on questions of moral responsibility to distinguish two different concepts, or senses, of moral responsibility via the labels ‘responsibility as attributability’ and ‘responsibility as accountability’. Gary Watson was perhaps the first to introduce this distinction in his influential 1996 article ‘Two Faces of Responsibility’ , but it has since been taken up by many other philosophers. My aim in this study is to raise some questions and doubts about this distinction and (...)
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  • The Mark of Responsibility.John Gardner - 2003 - Oxford Journal of Legal Studies 23 (2):157-171.
    This paper tackles three common misconceptions about responsibility. The first misconception is that it is against our interests to be responsible for our actions. The second is that our responsibility for our actions is fixed at the time when we act. The third is that we can only be responsible to someone in particular, not responsible full stop. The three misconceptions turn out to be related, and disabusing ourselves of them helps us to rediscover the most fundamental point of the (...)
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  • The Second Person Standpoint: Morality, Respect, and Accountability.Stephen L. Darwall - 1996 - Cambridge: Harvard University Press.
    The result is nothing less than a fundamental reorientation of moral theory that enables it at last to account for morality's supreme authority--an account that ...
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  • (1 other version)Hart and Feinberg on responsibility.John Gardner - 2008 - In Matthew H. Kramer (ed.), The legacy of H.L.A. Hart: legal, political, and moral philosophy. New York: Oxford University Press.
    Forthcoming in Kramer et al (eds), The Legacy of H.L.A. Hart. Posted 8 February 2008.
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  • Transhumanist Values.Nick Bostrom - 2005 - Journal of Philosophical Research 30 (Supplement):3-14.
    Transhumanism is a loosely defined movement that has developed gradually over the past two decades. [1] It promotes an interdisciplinary approach to understanding and evaluating the opportunities for enhancing the human condition and the human organism opened up by the advancement of technology. Attention is given to both present technologies, like genetic engineering and information technology, and anticipated future ones, such as molecular nanotechnology and artificial intelligence.
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  • Altered Inheritance: Crispr and the Ethics of Human Genome Editing.Françoise Baylis - 2019 - Cambridge, Massachusetts: Harvard University Press.
    With the advent of CRISPR gene-editing technology, designer babies have become a reality. Françoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.
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  • Imposing Risk: A Normative Framework.John Oberdiek - 2014 - Oxford University Press UK.
    We subject others and are ourselves subjected to risk all the time - risk permeates life. Despite the ubiquity of risk and its imposition, philosophers and legal scholars have devoted little of their attention to the difficult questions stimulated by the pervasiveness of risk. When we impose risk upon others, what is it that we are doing? What is risking's moral significance? What moral standards govern the imposition of risk? And how should the law respond to it? This book highlights (...)
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  • Philosophical Perspectives on Risk.Sven Ove Hansson - 2004 - Techné: Research in Philosophy and Technology 8 (1):10-35.
    In non-technical contexts, the word “risk” refers, often rather vaguely, to situations in which it is possible but not certain that some undesirable event will occur. In technical contexts, the word has many uses and specialized meanings. The most common ones are the following.
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  • A Right against Risk-Imposition and the Problem of Paralysis.Sune Holm - 2016 - Ethical Theory and Moral Practice 19 (4):917-930.
    In this paper I examine the prospects for a rights-based approach to the morality of pure risk-imposition. In particular, I discuss a practical challenge to proponents of the thesis that we have a right against being imposed a risk of harm. According to an influential criticism, a right against risk-imposition will rule out all ordinary activities. The paper examines two strategies that rights theorists may follow in response to this “Paralysis Problem”. The first strategy introduces a threshold for when a (...)
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  • Risk Impositions, Genuine Losses, and Reparability as a Moral Constraint.Madeleine Hayenhjelm - 2018 - Ethical Perspectives 25 (3):419-446.
    What kind of moral principle could be sufficiently restrictive to avoid the kind of large-scale risks that have resulted in catastrophe in the past, while at the same time not be so restrictive as to halt desirable progress? Is there such a principle that is not merely a precautionary principle, but one that could be based on firm moral grounds? In this article, I set out to explore a simple idea: might it be the case that reparability could serve as (...)
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  • Hypothetical Retrospection.Sven Ove Hansson - 2007 - Ethical Theory and Moral Practice 10 (2):145-157.
    Moral theory has mostly focused on idealized situations in which the morally relevant properties of human actions can be known beforehand. Here, a framework is proposed that is intended to sharpen moral intuitions and improve moral argumentation in problems involving risk and uncertainty. Guidelines are proposed for a systematic search of suitable future viewpoints for hypothetical retrospection. In hypothetical retrospection, a decision is evaluated under the assumption that one of the branches of possible future developments has materialized. This evaluation is (...)
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  • Rights, explanation, and risks.David McCarthy - 1997 - Ethics 107 (2):205-225.
    Theories of rights seem well equipped to explain widely accepted claims about the morality of harming. But can they explain popular claims about the morality of imposing risks of harm? Many think not. But a plausible theory of rights can explain those claims if it says we have the right that others not impose risks of harm upon us. That is a good reason to believe we have that right. There are many objections to the claim that we have that (...)
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  • Punishment, Communication, and Community.R. A. Duff - 2003 - Philosophical Quarterly 53 (211):310-313.
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  • Responsibility.John Randolph Lucas - 1995 - Oxford, GB: Clarendon Press.
    Responsibility is a key concept in our moral, social, and political thinking, but it is not itself properly understood. J.R. Lucas here presents a lively, broad, and accessible discussion of responsibility in various areas of human life, from personal and sexual relations to politics.
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  • Relational Reasons and the Criminal Law.R. A. Duff - 2013 - In Leiter B. & Green L. (eds.), Oxford Studies in Legal Philosophy, vol. 2. Oxford UP. pp. 175-208.
    First paragraph: Some reasons for action are relational. I have a relational reason to Φ when I have reason to Φ in virtue of a relationship in which I stand, or a role that I fill; absent that relationship or that role I would not have that reason to Φ ; others who do not stand in that relationship or fill that role do not have that reason to Φ . I have a relational reason to feed this child -- (...)
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  • Trust in Science: CRISPR–Cas9 and the Ban on Human Germline Editing.Stephan Guttinger - 2018 - Science and Engineering Ethics 24 (4):1077-1096.
    In 2015 scientists called for a partial ban on genome editing in human germline cells. This call was a response to the rapid development of the CRISPR–Cas9 system, a molecular tool that allows researchers to modify genomic DNA in living organisms with high precision and ease of use. Importantly, the ban was meant to be a trust-building exercise that promises a ‘prudent’ way forward. The goal of this paper is to analyse whether the ban can deliver on this promise. To (...)
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