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  1. Ghost management: How much of the medical literature is shaped behind the scenes by the pharmaceutical industry?Sergio Sismondo - manuscript
    Anecdotes have shown that some articles on profitable drugs are constructed by and shepherded through publication by pharmaceutical companies and their agents, whose influence is largely invisible to readers. This is ghost-management, the substantial but unrecognized research, analysis, writing, editing and/or facilitation behind publication. Publicly available documents suggest that these practices extremely widespread affecting up to 40% of clinical trial reports in key periods but it has been unclear how representative these documents are. This article presents the results of an (...)
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  • The Disposable Author: How Pharmaceutical Marketing Is Embraced within Medicine's Scholarly Literature.Alastair Matheson - 2016 - Hastings Center Report 46 (4):31-37.
    The best studies on the relationship between pharmaceutical corporations and medicine have recognized that it is an ambiguous one. Yet most scholarship has pursued a simpler, more saleable narrative in which pharma is a scheming villain and medicine its maidenly victim. In this article, I argue that such crude moral framing blunts understanding of the murky realities of medicine's relationship with pharma and, in consequence, holds back reform. My goal is to put matters right in respect to one critical area (...)
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  • Disclosure is Inadequate as a Solution to Managing Conflicts of Interest in Human Research.Helene Jacmon - 2018 - Journal of Bioethical Inquiry 15 (1):71-80.
    Disclosure is a common response to conflicts of interest; it is intended to expose the conflict to scrutiny and enable it to be appropriately managed. For disclosure to be effective the receiver of the disclosure needs to be able to use the information to assess how the conflict may impact on their interests and then implement a suitable response. The act of disclosure also creates an expectation of self-regulation, as the person with the conflicting interests will be mindful of their (...)
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  • Hooked: Ethics, the Medical Profession, and the Pharmaceutical Industry.Howard Brody - 2007 - Rowman & Littlefield Publishers.
    This book explores the controversial relationship between physicians and the pharmaceutical industry, identifies the ethical tensions and controversies, and proposes numerous reforms both for medicine's own professional integrity and for effective public regulation of the industry.
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  • Symposium Lead Essay—Conflict of Interest: Opening Up New Territories.Miriam Wiersma, Wendy Lipworth, Paul Komesaroff & Ian Kerridge - 2020 - Journal of Bioethical Inquiry 17 (2):169-172.
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  • Debates about Conflict of Interest in Medicine: Deconstructing a Divided Discourse.Serena Purdy, Miles Little, Christopher Mayes & Wendy Lipworth - 2017 - Journal of Bioethical Inquiry 14 (1):135-149.
    The pharmaceutical industry plays an increasingly dominant role in healthcare, raising concerns about “conflicts of interest” on the part of the medical professionals who interact with the industry. However, there is considerable disagreement over the extent to which COI is a problem and how it should be managed. Participants in debates about COI have become entrenched in their views, which is both unproductive and deeply confusing for the majority of medical professionals trying to work in an increasingly commercialized environment. We (...)
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  • Financial Conflicts of Interest at FDA Drug Advisory Committee Meetings.Michael J. Hayes & Vinay Prasad - 2018 - Hastings Center Report 48 (2):10-13.
    The U.S. Food and Drug Administration's drug advisory committees provide expert assessments of the safety and efficacy of new therapies considered for approval. A committee hears from a variety of speakers, from six groups, including voting members of the committee, FDA staff members, employees of the pharmaceutical company seeking approval of a therapy, patient and consumer representatives, expert speakers invited by the company, and public participants. The committees convene at the request of the FDA when the risks and harms of (...)
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