Two protechnology arguments, the “hopeful principle” and the “automatic escalator”, often used in bioethics, are identified and critically analysed in this paper. It is shown that the hopeful principle is closely related to the problematic precautionary principle, and the automatic escalator argument has close affinities to the often criticised empirical slippery slope argument. The hopeful principle is shown to be really hopeless as an argument, and automatic escalator arguments often lead nowhere when critically analysed. These arguments should therefore only be (...) used with great caution. (shrink)

In this paper I analyse who should be able to control the use of human embryonic stem cell lines. I distinguish between different kinds of control and analyse a set of arguments that purport to show that the donors of gametes and embryos should not be able to control the use of stem cell lines derived from their embryos. I show these arguments to be either deficient or of so general a scope that they apply not only to donors but (...) also to those who derived the stem cell lines. Since we normally think that stem cell derivers have the right to control the use of the cell lines they derived, we have no justification for denying donors similar rights of control. In the final section I briefly discuss why informed consent is not an appropriate vehicle for transferring or alienating control rights. (shrink)

Biobank research is potentially fruitful. It is argued that broad consent is acceptable for future research on biological material because a) the benefit is high, b) it pays respect to people’s autonomy, c) it is consistent with current practices and d) because the risk is low. Furthermore, broad consent should be allowed if information is handled safely, people can withdraw and expanded research should be approved by an ethics review board. However, these arguments are flawed and the criteria for broad (...) consent are either too restrictive to allow any research or fail to address important challenges with biobank research. Broad consent for biobank research can hide substantial ethical challenges and threaten trust in research. This does not mean that biobank research should be abandoned or that people cannot authorise future research on donated biological material. (shrink)

What is life? For four centuries, it has been believed that the only possible scientific approach to this question proceeds from the Cartesian metaphor -- organism as machine. Therefore, organisms are to be studied and characterized the same way "machines" are; the same way any inorganic system is. Robert Rosen argues that such a view is neither necessary nor sufficient to answer the question. He asserts that life is not a specialization of mechanism, but rather a sweeping generalization of it. (...) Above all, Rosen argues that renouncing mechanism does not mean abandoning science. A radical alternative is proposed, drawn equally from experience in biology, physics, and mathematics; an alternative which draws attention to a new class of complex systems, which are radically different from mechanism. (shrink)

Georges Canguilhem is one of France's foremost historians of science. Trained as a medical doctor as well as a philosopher, he combined these practices to demonstrate to philosophers that there could be no epistemology without concrete study of the actual development of the sciences and to historians that there could be no worthwhile history of science without a philosophical understanding of the conceptual basis of all knowledge. A Vital Rationalist brings together for the first time a selection of Canguilhem's most (...) important writings, including excerpts from previously unpublished manuscripts and a critical bibliography by Camille Limoges. Organized around the major themes and problems that have preoccupied Canguilhem throughout his intellectual career, the collection allows readers, whether familiar or unfamiliar with Canguilhem's work, access to a vast array of conceptual and concrete meditations on epistemology, methodology, science, and history. Canguilhem is a demanding writer, but Delaporte succeeds in marking out the main lines of his thought with unrivaled clarity; readers will come away with a heightened understanding of the complex and crucial place he holds in French intellectual history. (shrink)