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  1. Exploratory Experimentation and Scientific Practice: Metagenomics and the Proteorhodopsin Case.Maureen O'Malley - 2007 - History and Philosophy of the Life Sciences 29 (3):337 - 360.
    Exploratory experimentation and high-throughput molecular biology appear to have considerable affinity for each other. Included in the latter category is metagenomics, which is the DNA-based study of diverse microbial communities from a vast range of non-laboratory environments. Metagenomics has already made numerous discoveries and these have led to reinterpretations of fundamental concepts of microbial organization, evolution, and ecology. The most outstanding success story of metagenomics to date involves the discovery of a rhodopsin gene, named proteorhodopsin, in marine bacteria that were (...)
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  • Rethinking the role of theory in exploratory experimentation.David Colaço - 2018 - Biology and Philosophy 33 (5-6):38.
    To explain their role in discovery and contrast them with theory-driven research, philosophers of science have characterized exploratory experiments in terms of what they lack: namely, that they lack direction from what have been called “local theories” of the target system or object under investigation. I argue that this is incorrect: it’s not whether or not there is direction from a local theory that matters, but instead how such a theory is used to direct an experiment that matters. Appealing to (...)
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  • Recent work on Kantian maxims I: Established approaches.Rob Gressis - 2010 - Philosophy Compass 5 (3):216-227.
    Maxims play a crucial role in Kant's ethical philosophy, but there is significant disagreement about what maxims are. In this two-part essay, I survey eight different views of Kantian maxims, presenting their strengths, and their weaknesses. Part I: Established Approaches, begins with Rüdiger Bubner's view that Kant took maxims to be what ordinary people of today take them to be, namely pithily expressed precepts of morality or prudence. Next comes the position, most associated with Rüdiger Bittner and Otfried Höffe, that (...)
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  • Review: The New Experimentalism. [REVIEW]Robert Ackermann - 1989 - British Journal for the Philosophy of Science 40 (2):185 - 190.
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  • Varieties of Exploratory Experimentation in Nanotoxicology.Kevin Elliott - 2007 - History and Philosophy of the Life Sciences 29 (3):313 - 336.
    There has been relatively little effort to provide a systematic overview of different forms of exploratory experimentation (EE). The present paper examines the growing subdiscipline of nanotoxicology and suggests that it illustrates at least four ways that researchers can engage in EE: searching for regularities; developing new techniques, simulation models, and instrumentation; collecting and analyzing large swaths of data using new experimental strategies (e.g., computer-based simulation and "high-throughput" instrumentation); and structuring an entire disciplinary field around exploratory research agendas. In order (...)
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  • A case study in experimental exploration: exploratory data selection at the Large Hadron Collider.Koray Karaca - 2017 - Synthese 194 (2):333-354.
    In this paper, I propose an account that accommodates the possibility of experimentation being exploratory in cases where the procedures necessary to plan and perform an experiment are dependent on the theoretical accounts of the phenomena under investigation. The present account suggests that experimental exploration requires the implementation of an exploratory procedure that serves to extend the range of possible outcomes of an experiment, thereby enabling it to pursue its objectives. Furthermore, I argue that the present account subsumes the notion (...)
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  • “Exploratory experimentation” as a probe into the relation between historiography and philosophy of science.Jutta Schickore - 2016 - Studies in History and Philosophy of Science Part A 55:20-26.
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  • Mechanical science on the factory floor: The early industrial revolution in leeds.Margaret C. Jacob - 2007 - History of Science 45 (2):197-222.
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  • Exploratory Experimentation and the Role of Histochemical Techniques in the Work of Jean Brachet, 1938-1952.Richard M. Burian - 1997 - History and Philosophy of the Life Sciences 19 (1):27 - 45.
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  • Experiments in history and philosophy of science.Friedrich Steinle - 2002 - Perspectives on Science 10 (4):408-432.
    : The increasing attention on experiment in the last two decades has led to important insights into its material, cultural and social dimensions. However, the role of experiment as a tool for generating knowledge has been comparatively poorly studied. What questions are asked in experimental research? How are they treated and eventually resolved? And how do questions, epistemic situations, and experimental activity cohere and shape each other? In my paper, I treat these problems on the basis of detailed studies of (...)
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  • “The joint labours of ingenious men”: J ohn S meaton's R oyal S ociety network and the E ddystone L ighthouse.Andrew M. A. Morris - 2021 - Centaurus 63 (3):513-531.
    The Industrial Enlightenment is widely thought to have been a period when “science” and “technology” became intimately intertwined. In his 1791 book on the building of the Eddystone lighthouse (completed in 1759), the English engineer John Smeaton praised the Royal Society for being more than a group of abstract theoreticians. This article looks at the fellows of Smeaton's Royal Society network who contributed knowledge, reports, specimens, and inventions solicited by Smeaton when he was working on this lighthouse project. I show, (...)
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  • John Smeaton and the vis viva controversy: Measuring waterwheel efficiency and the influence of industry on practical mechanics in Britain 1759–1808.Andrew M. A. Morris - 2018 - History of Science 56 (2):196-223.
    In this paper, I will examine John Smeaton’s contribution to the vis viva controversy in Britain, focusing on how the hybridization of science, technology, and industry helped to establish vis viva, or mechanic power, as a measure of motive force. Smeaton, embodying the ‘hybrid expert’ who combined theoretical knowledge and practical knowhow, demonstrated that the notion of vis viva possessed a greater explanatory power than momentum, because it could be used to explain the difference in efficiency between overshot and undershot (...)
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  • Experimental Spaces and the Knowledge Economy.L. Stewart - 2007 - History of Science 45 (2):155-177.
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