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How necessary are randomized controlled trials?

In Ronald Munson (ed.), Intervention and Reflection: Basic Issues in Medical Ethics. pp. 187-191 (1992)

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  1. Why There’s No Cause to Randomize.John Worrall - 2007 - British Journal for the Philosophy of Science 58 (3):451-488.
    The evidence from randomized controlled trials (RCTs) is widely regarded as supplying the ‘gold standard’ in medicine—we may sometimes have to settle for other forms of evidence, but this is always epistemically second-best. But how well justified is the epistemic claim about the superiority of RCTs? This paper adds to my earlier (predominantly negative) analyses of the claims produced in favour of the idea that randomization plays a uniquely privileged epistemic role, by closely inspecting three related arguments from leading contributors (...)
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  • (1 other version)What evidence in evidence-based medicine?John Worrall - 2002 - Proceedings of the Philosophy of Science Association 2002 (3):S316-S330.
    Evidence-Based Medicine is a relatively new movement that seeks to put clinical med- icine on a firmer scientific footing. I take it as uncontroversial that medical practice should be based on best evidence-the interesting questions concern the details. This paper tries to move towards a coherent and unified account of best evidence in medicine, by exploring in particular the EBM position on RCTs (randomized controlled trials).
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  • (1 other version)What Evidence in Evidence‐Based Medicine?John Worrall - 2002 - Philosophy of Science 69 (S3):S316-S330.
    Evidence-Based Medicine is a relatively new movement that seeks to put clinical medicine on a firmer scientific footing. I take it as uncontroversial that medical practice should be based on best evidence—the interesting questions concern the details. This paper tries to move towards a coherent and unified account of best evidence in medicine, by exploring in particular the EBM position on RCTs.
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