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  1. Ethical issues in using a cocaine vaccine to treat and prevent cocaine abuse and dependence.W. Hall - 2004 - Journal of Medical Ethics 30 (4):337-340.
    A “cocaine vaccine” is a promising immunotherapeutic approach to treating cocaine dependence which induces the immune system to form antibodies that prevent cocaine from crossing the blood brain barrier to act on receptor sites in the brain. Studies in rats show that cocaine antibodies block cocaine from reaching the brain and prevent the reinstatement of cocaine self administration. A successful phase 1 trial of a human cocaine vaccine has been reported. The most promising application of a cocaine vaccine is to (...)
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  • Cynthia's dilemma: Consenting to heroin prescription.Louis C. Charland - 2002 - American Journal of Bioethics 2 (2):37-47.
    Heroin prescription involves the medical provision of heroin in the treatment of heroin addiction. Rudimentary clinical trials on that treatment modality have been carried out and others are currently underway or in development. However, it is questionable whether subjects considered for such trials are mentally competent to consent to them. The problem has not been sufficiently appreciated in ethical and clinical discussions of the topic. The challenges involved throw new light on the role of value and accountability in contemporary discussions (...)
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