William Uttal is concerned that in an effort to prove itself a hard science, psychology may have thrown away one of its most important methodological tools—a critical analysis of the fundamental assumptions that underlie day-to-day empirical research. In this book Uttal addresses the question of localization: whether psychological processes can be defined and isolated in a way that permits them to be associated with particular brain regions. New, noninvasive imaging technologies allow us to observe the brain while it is actively (...) engaged in mental activities. Uttal cautions, however, that the excitement of these new research tools can lead to a neuroreductionist wild goose chase. With more and more cognitive neuroscientific data forthcoming, it becomes critical to question their limitations as well as their potential. Uttal reviews the history of localization theory, presents the difficulties of defining cognitive processes, and examines the conceptual and technical difficulties that should make us cautious about falling victim to what may be a "neo-phrenological" fad. (shrink)

was to test the role of both early and higher visual areas in the integration of local features into global shapes. To this end, we conducted functional magnetic resonance imaging studies. Although fMRI lacks the high spatial resolution of intracortical recordings, it allows simultaneous collection of responses to the same stimulus set from multiple visual areas that is not possible with standard recording techniques. We performed these studies in monkeys, where much is known about the properties of neurons in different (...) visual areas, and in humans, where recent fMRI.. (shrink)

The method of positron emission tomography illustrates the circular logic popular in subtractive neuroimaging and linear reductive cognitive psychology. Both require that strictly feed-forward, modular, cognitive components exist, before the fact, to justify the inference of particular components from images after the fact. Also, both require a "true" componential theory of cognition and laboratory tasks, before the fact, to guarantee reliable choices for subtractive contrasts. None of these possibilities are likely. Consequently, linear reductive analysis has failed to yield general, reliable, (...) componential accounts. (shrink)

The method of positron emission tomography (PET imaging) illustrates the circular logic popular in subtractive neuroimaging and linear reductive cognitive psychology. Both require that strictly feed-forward, modular, cognitive components exist, before the fact, to justify the inference of particular components from images (or other observables) after the fact. Also, both require a "true" componential theory of cognition and laboratory tasks, before the fact, to guarantee reliable choices for subtractive contrasts. None of these possibilities are likely. Consequently, linear reductive analysis has (...) failed to yield general, reliable, componential accounts. (shrink)

The need to align multiple experimental procedures and produce converging results so as to demonstrate that the phenomenon under investigation is real and not an artifact is a commonplace both in scientific practice and discussions of scientific methodology (Campbell and Stanley 1963; Wimsatt 1981). Although sometimes this is the purpose of aligning techniques, often there is a different purpose—multiple techniques are sought to supply different perspectives on the phenomena under investigation that need to be integrated to answer the questions scientists (...) are asking. After introducing this function, I will illustrate it by considering three of the major techniques in cognitive neuroscience for linking cognitive function with neural structure. (shrink)

Running head: Functional neuroimaging Abstract Several recently developed techniques enable the investigation of the neural basis of cognitive function in the human brain. Two of these, PET and fMRI, yield whole-brain images reflecting regional neural activity associated with the performance of specific tasks. This article explores the spatial and temporal capabilities and limitations of these techniques, and discusses technical, biological, and cognitive issues relevant to understanding the goals and methods of neuroimaging studies. The types of advances in understanding cognitive and (...) brain function made possible with these methods are illustrated with examples from the neuroimaging literature. (shrink)

The method of positron emission tomography illustrates the circular logic popular in subtractive neuroimaging and linear reductive cognitive psychology. Both require that strictly feed-forward, modular, cognitive components exist, before the fact, to justify the inference of particular components from images after the fact. Also, both require a "true" componential theory of cognition and laboratory tasks, before the fact, to guarantee reliable choices for subtractive contrasts. None of these possibilities are likely. Consequently, linear reductive analysis has failed to yield general, reliable, (...) componential accounts. (shrink)

The method of positron emission tomography illustrates the circular logic popular in subtractive neuroimaging and linear reductive cognitive psychology. Both require that strictly feed-forward, modular, cognitive components exist, before the fact, to justify the inference of particular components from images after the fact. Also, both require a "true" componential theory of cognition and laboratory tasks, before the fact, to guarantee reliable choices for subtractive contrasts. None of these possibilities are likely. Consequently, linear reductive analysis has failed to yield general, reliable, (...) componential accounts. (shrink)

We have used fMRI to measure responses to chromatic and achromatic contrast in retinotopically defined regions of macaque and human visual cortex. We make four observations. Firstly, the relative amplitudes of responses to color and luminance stimuli in macaque area V1 are similar to those previously observed in human fMRI experiments. Secondly, the dorsal and ventral subdivisions of macaque area V4 respond in a similar way to opponent (L j M)-cone chromatic contrast suggesting that they are part of a single (...) functional area. Thirdly, we find that macaque area V4, like area V1, responds preferentially to chromatic contrast compared to luminance contrast and the degree of preference is strongly influenced by the temporal frequency of the stimulus. Finally, we observe that while macaque V4d is a region on the dorsal surface of the macaque visual cortex that responds robustly to chromatic stimuli, human chromatic responses to identical stimuli are largely confined to the ventral surface suggesting a fundamental difference in the topographical organization of higher visual areas between humans and macaques. (shrink)