Serological data have been used to address anthropological problems since the turn of the century. These were predominantly problems of two kinds in anthropological systematics: the relations of human populations to one another (racial serology), and the relations of primate species to one another (systematic serology). Though they were the locus of considerable debate about the relative merits of 'genetic' versus 'traditional' data, the serological work had little lasting impact in the field. I attribute this to the fact that the (...) research was carried out largely externally to anthropology, and often interpreted in facile manners. To a large extent the history of this research has been ignored or rewritten following the development of 'molecular anthropology' in the 1960s. To some extent, however, contemporary genetic research in anthropology replays aspects of the serological era. (shrink)