The term ‘mechanism’ has been used in two quite different ways in the history of biology. Operative, or explanatory mechanism refers to the step-by-step description or explanation of how components in a system interact to yield a particular outcome . Philosophical Mechanism, on the other hand, refers to a broad view of organisms as material entities, functioning in ways similar to machines — that is, carrying out a variety of activities based on known chemical and physical processes. In the early (...) twentieth century philosophical Mechanism became the foundation of a ‘new biology’ that sought to establish the life sciences on the same solid and rigorous foundation as the physical sciences, including a strong emphasis on experimentation. In the context of the times this campaign was particularly aimed at combating the reintroduction of more holistic, non-mechanical approaches into the life sciences . In so doing, Mechanists failed to see some of the strong points of non-vitalistic holistic thinking. The two approaches are illustrated in the work of Jacques Loeb and Hans Spemann. (shrink)

In the sixteenth century the Stoics were deemed friends of humanist Christians, but by the eighteenth century they were attacked as atheists. What happened in the intervening period? In the middle of this period falls Ralph Cudworth’s True Intellectual System of the Universe (1678), which contains a sustained analysis of Stoic theology. In Cudworth’s complex taxonomy Stoicism appears twice, both as a form of atheism and an example of imperfect theism. Whether the Stoics are theists or atheists hinges on whether (...) their God is conscious and intelligent, or alive but unconscious like a plant or vegetable. Is God sentient or is he a mindless vegetable? (shrink)