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  1. Patients’ Beliefs About Deep Brain Stimulation for Treatment-Resistant Depression.Ryan E. Lawrence, Catharine R. Kaufmann, Ravi B. DeSilva & Paul S. Appelbaum - 2018 - American Journal of Bioethics Neuroscience 9 (4):210-218.
    Deep brain stimulation is an experimental procedure for treatment-resistant depression. Some results show promise, but blinded trials had limited success. Ethical questions center on vulnerability: especially on whether depressed patients can weigh the risks and benefits effectively, whether depression causes “desperation,” and whether media portrayals create unrealistic hopes. We interviewed 24 psychiatric inpatients with treatment-resistant depression, qualitatively analyzing their comments. Most had minimal interest in deep brain stimulators. Some might consider them if their depression worsened, if alternatives were exhausted, or (...)
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  • Are Mental Disorders Natural Kinds?: A Plea for a New Approach to Intervention in Psychiatry.Şerife Tekin - 2016 - Philosophy, Psychiatry, and Psychology 23 (2):147-163.
    Mental disorder is an urgent and growing public health problem.1 Scientific investigation of this problem has the pragmatic goals of identifying the causes of mental disorders and developing strategies to effectively treat them. Philosophers of psychiatry have participated in the inquiry into the empirical examination of mental disorders, predominantly by debating whether psychopathology is a legitimate target of scientific inquiry and, if so, how mental disorders should be explained, predicted, and intervened on. However, as I show in this paper, these (...)
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  • Hyponarrativity and Context-Specific Limitations of the DSM-5.Şerife Tekin & Melissa Mosko - 2015 - Public Affairs Quarterly 29 (1).
    his article develops a set of recommendations for the psychiatric and medical community in the treatment of mental disorders in response to the recently published fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, that is, DSM-5. We focus primarily on the limitations of the DSM-5 in its individuation of Complicated Grief, which can be diagnosed as Major Depression under its new criteria, and Post-Traumatic Stress Disorder (PTSD). We argue that the hyponarrativity of the descriptions of these disorders (...)
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  • Against the Drug Cure Model: Addiction, Identity, and Pharmaceuticals.Şerife Tekin, Owen Flanagan & George Graham - 2017 - In Dien Ho (ed.), Philosophical Issues in Pharmaceutics: Development, Dispensing, and Use. Dordrecht: Springer.
    Recent advances in brain imaging methods as well as increased sophistication in neuroscientific modeling of the brain’s reward systems have facilitated the study of neural mechanisms associated with addiction such as processes associated with motivation, decision-making, pleasure seeking, and inhibitory control. These scientific activities have increased optimism that the neurological underpinnings of addiction will be delineated, and that pharmaceuticals that target and change these mechanisms will by themselves facilitate early intervention and even full recovery. In this paper, we argue that (...)
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  • Self-Insight in the Time of Mood Disorders: After the Diagnosis, Beyond the Treatment.Serife Tekin - 2014 - Philosophy, Psychiatry, and Psychology 21 (2):139-155.
    This paper explores the factors that contribute to the degree of a mood disorder patient’s self- insight, defined here as her understanding of the particular contingencies of her life that are responsive to her personal identity, interpersonal relationships, illness symptoms, and the relationship between these three necessary components of her lived experience. I consider three factors: (i) the Diagnostic Statistical Manual of Mental Disorders (DSM), (ii) the DSM culture, and (iii) the cognitive architecture of the self. I argue that the (...)
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