In the history of science the ‘Elixir Tychonis’ was rather neglected till today. This elixir consists of three prescriptions. The first was published in Cista medica by Thomas Bartholinus, the third in the biography of Brahe written by Gassendi . The famous edition of Opera omnia Brahei by Dreyer contains the three prescriptions in the Vol. IX; Dreyer used only the manuscript Langebekiana Nr. 179 under consideration of the printed texts differing from the manuscript. The discovery of the probable unknown (...) original text for the printed text in Cista medica was made by us in the University Library of Basle; by further inquiries were found two neglected manuscripts in the University Library of Erlangen. We restricted our examinations not only to palaeographical comparison of the three new manuscripts but we extended also the historical analysis to the interpretation of the underlying alchemical ideas of Tycho Brahe. In the history of chemistry the ‘chymist’ Brahe is rather unknown; therefore it seemed necessary to show by comparison with the original contemporary sources the position of our Danish astronomer towards Paracelsism in the sixteenth and seventeenth centuries. (shrink)