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Kunjumon Vadakkan [4] Vadakkan [1]
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Kunjumon Vadakkan
University of Manitoba
  1. A Pressure-Reversible Cellular Mechanism of General Anesthetics Capable of Altering a Possible Mechanism of Consciousness.Kunjumon Vadakkan - 2015 - Springerplus 4:1-17.
    Different anesthetics are known to modulate different types of membrane-bound receptors. Their common mechanism of action is expected to alter the mechanism for consciousness. Consciousness is hypothesized as the integral of all the units of internal sensations induced by reactivation of inter-postsynaptic membrane functional LINKs during mechanisms that lead to oscillating potentials. The thermodynamics of the spontaneous lateral curvature of lipid membranes induced by lipophilic anesthetics can lead to the formation of non-specific inter-postsynaptic membrane functional LINKs by different mechanisms. These (...)
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  2. Framework of Consciousness From Semblance of Activity at Functionally LINKed Postsynaptic Membranes.Kunjumon Vadakkan - 2010 - Frontiers in Consciousness Research 1 (1):1-12.
    Consciousness is seen as a difficult “binding” problem. Binding, a process where different sensations evoked by an item are associated in the nervous system, can be viewed as a process similar to associative learning. Several reports that consciousness is associated with some form of memory imply that different forms of memories have a common feature contributing to consciousness. Based on a proposed synaptic mechanism capable of explaining different forms of memory, we developed a framework for consciousness. It is based on (...)
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  3. Substantive Nature of Sleep in Updating the Temporal Conditions Necessary for Inducing Units of Internal Sensations.Kunjumon Vadakkan - 2016 - Sleep Science 9.
    Unlike other organs that operate continuously, such as the heart and kidneys, many of the operations of the nervous system shut down during sleep. The evolutionarily conserved unconscious state of sleep that puts animals at risk from predators indicates that it is an indispensable integral part of systems operation. A reasonable expectation is that any hypothesis for the mechanism of the nervous system functions should be able to provide an explanation for sleep. In this regard, the semblance hypothesis is examined. (...)
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  4. A Framework for the First‑Person Internal Sensation of Visual Perception in Mammals and a Comparable Circuitry for Olfactory Perception in Drosophila.Kunjumon Vadakkan - 2015 - Springerplus 4 (833):1-23.
    Perception is a first-person internal sensation induced within the nervous system at the time of arrival of sensory stimuli from objects in the environment. Lack of access to the first-person properties has limited viewing perception as an emergent property and it is currently being studied using third-person observed findings from various levels. One feasible approach to understand its mechanism is to build a hypothesis for the specific conditions and required circuit features of the nodal points where the mechanistic operation of (...)
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  5. Framework of Consciousness From Semblance of Activity at Functionally LINKed Postsynaptic Membranes. Vadakkan - 2010 - Frontiers in Conssciousness Research 1 (1):1-12.
    Consciousness is seen as a difficult “binding” problem. Binding, a process where different sensations evoked by an item are associated in the nervous system, can be viewed as a process similar to associative learning. Several reports that consciousness is associated with some form of memory imply that different forms of memories have a common feature contributing to consciousness. Based on a proposed synaptic mechanism capable of explaining different forms of memory, we developed a framework for consciousness. It is based on (...)
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