Results for ' optogenetics'

6 found
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  1. Optogenetics, Pluralism, and Progress.Jacqueline Anne Sullivan - 2018 - Philosophy of Science 85 (00):1090-1101.
    Optogenetic techniques are described as “revolutionary” for the unprecedented causal control they allow neuroscientists to exert over neural activity in awake behaving animals. In this paper, I demonstrate by means of a case study that optogenetic techniques will only illuminate causal links between the brain and behavior to the extent that their error characteristics are known and, further, that determining these error characteristics requires comparison of optogenetic techniques with techniques having well known error characteristics and consideration of the broader neural (...)
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  2. Optogenetic Memory Modification and the Many Facets of Authenticity.Alexandre Erler - 2021 - American Journal of Bioethics Neuroscience 12 (1):40-42.
    Open Peer Commentary on P. Zawadzki and A. K. Adamczyk's target article in AJOB Neuroscience on the potential of optogenetics for memory modification. I argue for a radically pluralistic understanding of the notion of authenticity, and highlight the need to further clarify the specific nature of the authors' concern about authenticity, as well as its policy implications.
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  3. The Memory-Modifying Potential of Optogenetics and the Need for Neuroethics.Agnieszka K. Adamczyk & Przemysław Zawadzki - 2020 - NanoEthics 14 (3):207-225.
    Optogenetics is an invasive neuromodulation technology involving the use of light to control the activity of individual neurons. Even though optogenetics is a relatively new neuromodulation tool whose various implications have not yet been scrutinized, it has already been approved for its first clinical trials in humans. As optogenetics is being intensively investigated in animal models with the aim of developing novel brain stimulation treatments for various neurological and psychiatric disorders, it appears crucial to consider both the (...)
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  4. Personality and Authenticity in Light of the Memory-Modifying Potential of Optogenetics.Przemysław Zawadzki & Agnieszka K. Adamczyk - 2021 - American Journal of Bioethics Neuroscience 12 (1):3-21.
    There has been a growing interest in research concerning memory modification technologies (MMTs) in recent years. Neuroscientists and psychologists are beginning to explore the prospect of controllable and intentional modification of human memory. One of the technologies with the greatest potential to this end is optogenetics—an invasive neuromodulation technique involving the use of light to control the activity of individual brain cells. It has recently shown the potential to modify specific long-term memories in animal models in ways not yet (...)
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  5. Personality and Authenticity in Light of the Memory-Modifying Potential of Optogenetics: A Reply to Objections about Potential Therapeutic Applicability of Optogenetics.Agnieszka K. Adamczyk & Przemysław Zawadzki - 2021 - American Journal of Bioethics Neuroscience 15 (2):W4-W7.
    In our article (Zawadzki and Adamczyk 2021), we analyzed threats that novel memory modifying interventions may pose in the future. More specifically, we discussed how optogenetics’ potential for reversible erasure/deactivation of memory “may impact authenticity by producing changes at different levels of personality.” Our article has received many thoughtful open peer commentaries for which we would like to express our great appreciation. We have identified two main threads of objections. They are related to the potential applicability of optogenetics (...)
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  6. To remember, or not to remember? Potential impact of memory modification on narrative identity, personal agency, mental health, and well-being.Przemysław Zawadzki - 2021 - Bioethics 35 (9):891-899.
    Memory modification technologies (MMTs)—interventions within the memory affecting its functions and contents in specific ways—raise great therapeutic hopes but also great fears. Ethicists have expressed concerns that developing and using MMTs may endanger the very fabric of who we are—our personal identity. This threat has been mainly considered in relation to two interrelated concerns: truthfulness and narrative self‐constitution. In this article, we propose that although this perspective brings up important matters concerning the potential aftermaths of MMT utilization, it fails to (...)
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