Background: Ananas comosus Linn is famous in traditional medicine f o r i t s abortificant and anti inflammatory effects. Its peel is already e valuated and established as a remarkable antioxidant agent. Despite its intensive use in number of conditions, its neuropharmacological studies are still missing. So this study was performed (1) to analyze the qualitative phytochemical composition of methanolic extract of Ananas comosus Linn peel, and (2) To evaluate the antidepressant-like effects at different doses. (...) Methodology: Phytochemical screening of MeACP was performed by using standard chemicals and methods. 60 NMRI mice of either sex were randomly divided into Control group which received 5% Tween 80, a standard group which received Imipramine (15mg/kg) and three treatment groups which were given three doses 3.25, 7.5 and 15 mg/kg doses of MeACP. Antidepressant effects were measured in the forced swimming and tail suspension tests. Each group consisted of 6-7 animals. Result: All three test doses of MeACP (3.25, 7.5 and 15 mg/kg) induced antidepressant-like behavior in FST and TST (p<0.001) and comparable with positive control Imipramine 15mg/kg. Conclusions: Methanolic extract of MeACP possess excellent antidepressant potential at low doses but its effect on long term administration and its safety profile in acute and chronic administration is needed to be further evaluated,. (shrink)

Abstract: Background: The pineapple (A nanas comosus) is a tropical plant with an edible multiple fruit consisting of coalesced berries, also called pineapples, and the most economically significant plant in the Bromeliaceae family. Pineapples may be cultivated from a crown cutting of the fruit, possibly flowering in five to ten months and fruiting in the following six months.[5][6] Pineapples do not ripen significantly after harvest. In 2016, Costa Rica, Brazil, and the Philippines accounted for nearly one-third of the world's (...) production of pineapples.[8] Pineapple damage is not taken quickly, it can lead to damage in the Pineapple. Objectives: The main goal of this expert system is to get the appropriate diagnosis of disease and the correct treatment. Methods: In this paper the design of the proposed Expert System which was produced to help Fruits Agricultural Specialist in diagnosing many of the Pineapple diseases such as : Phytophthora heart (top) rot, Base (butt) rot or Fruit let core rot (green eye, Pineapple Sprain, Turf Toe, Pineapple disease , Plantar Fasciitis, Warts, Bunion, Rheumatoid Arthritis, Gout, Heel Spur, Athlete's Pineapple , The proposed expert system presents an overview about Pineapple diseases are given, the cause of diseases are outlined and the treatment of disease whenever possible is given out. CLIPS Expert System language was used for designing and implementing the proposed expert system. Results: The proposed Pineapple diseases diagnosis expert system was evaluated by Agricultural students and they were satisfied with its performance. Conclusions: The Proposed expert system is very useful for Fruits Agricultural Specialist, patients with Pineapple problem and newly graduated Agricultural Specialist. (shrink)