Qualia are defined as subjective or private feelings associated with sensory and other experiences. This article argues that private feelings might be expressed by or in a personal brain and discusses possible neurobiological implications. Four issues are considered: Functional dualism implies that mental functions are realized as emergent properties of the brain. In practice, functional dualism is compatible with both substance dualism and pan-psychism. The (adult) human brain is the product of biological and environmental processes, including cultural influences, and is (...) individually unique. Part of the cerebral neuronal processing is molded by individual memories and previous experiences. Biological processes underlying the realization of qualia, including neural activities, escape conscious control. The temporal expression of qualia is in part consciously channeled by, for instance, actual situations and cultural habits. Neuroscientific explanations refer to general principles of nature, rather than to individual phenomena. Hence, future neurobiological approaches might aim to identify which neuronal processes are involved in qualia and how. It seems illusory to explain each quale. (shrink)

This essay examines the relationship between metabolic brain processes and psycho-physiological activities or mental activity. It is argued that metabolic brain processes, including those involved in the production of energy, proteins and other molecules are restorative and conditional, rather than directly involved in mental activities. This stance suggests that life-time acquired learning and memory is precipitated as a permanent and personal configuration of the brain, that is in principle accessible to neurophysiological examination. Current neuroscience largely ignores implicitly or explicitly the (...) search for new emergent configurations of the brain. (shrink)

The essay questions the role of neurons in the concept of mind. The mind is considered as an emerging but physical property of the brain: a mental brain configuration does exist. This configuration is relatively resistant to brain damage, coma, hypoxia and normal (electro)physiological brain states and is envisioned as a relatively stable (nearly anatomical) structure. Consistent with this idea is that, despite the lifetime turnover of their constituents (e.g. proteins and nucleotides) and morphological changes, brain neurons do not divide. (...) Brain neurons are continuously modified, for example by lifetime experiences: genetic and epigenetic support for this thesis is provided. The presumed mental brain configuration guarantees lifetime storage of information, but does not imply that this information and memories remain unmodified during aging. In principle, neurons permanently affected by mental processes can be identified in vitro or in vivo, despite anticipated practical problems. This essay may help to scientifically legitimate complementary neurobiological ad psychotherapeutic approaches in psychiatry. (shrink)

In “Qualia in a Contemporary Neurobiological Perspective”, Korf tackles the perennial issue of qualia in the philosophy of mind. His discussion is partly a response to Chalmers’ hard problem, which, as evidenced by other recent discussions in Dialogues, remains fresh after nearly two decades. Korf highlights the importance of regarding each brain as a particular shaped by unique contingencies and suggests how neurobiological research might proceed in light of this. However, I argue that his discussion does not address (...) what is at the core of Chalmers’ hard problem, and so fails to bridge the gap between neurobiological processes and qualia. (shrink)