A long historiographical tradition has claimed that the famous Pietro Pomponazzi’s Tractatus de immortalitate animae had been inspired by Tommaso de Vio’s Commentary on De anima – whose basic thesis was that, according to the principles of Aristotelian philosophy, the human soul was mortal – even though Pomponazzi in his entire work never mentioned Caietanus as a model. Firstly, this article frames the status quaestionis focusing on affinities and divergences between the two books and on the possible relationship and exchange (...) between the two authors, especially on the topic of the Aristotelian psychology. Secondly, the present study shows what emerges from a cross-reading of the sources which includes the collection of the Opuscula published in 1519 by the Dominican friar Bartolomeo Spina, who explicitly accused Caietanus of having paved the way for the scandalous and anti-Christian Pomponazzi’s position. The important gain of this collation of texts is the discovery of an unseen moment of debate with Caietanus inside Pomponazzi’s Tractatus. (shrink)