We prove two theorems concerning indestructibility properties of the first two strongly compact cardinals when these cardinals are in addition the first two measurable cardinals. Starting from two supercompact cardinals $\kappa _1 < \kappa _2$, we force and construct a model in which $\kappa _1$ and $\kappa _2$ are both the first two strongly compact and first two measurable cardinals, $\kappa _1$ ’s strong compactness is fully indestructible, and $\kappa _2$ ’s strong compactness is indestructible under $\mathrm {Add}$ for any (...) ordinal $\delta $. This provides an answer to a strengthened version of a question of Sargsyan found in [17, Question 5]. We also investigate indestructibility properties that may occur when the first two strongly compact cardinals are not only the first two measurable cardinals, but also exhibit nontrivial degrees of supercompactness. (shrink)