During the past several decades, many epistemologists have argued for and contributed to a paradigm shift according to which knowledge is central to assertion, action, and interaction. This general position stands in sharp contrast to several recently developed accounts regarding specific epistemic contexts. These specific accounts resist applying traditional epistemic norms, including strong knowledge norms, to real-world situations of interest. In particular, I consider recent arguments about the epistemic standards for scientific pronouncements, expert testimony in a political context, and interactive (...) reasoning. I argue, firstly, that knowledge does have a crucial role to play in each case, contrary to appearances. Clarifying the role of knowledge fills gaps in our understanding left open by the existing accounts. Secondly, I show that combining the insights from the knowledge-centric approach and from the more specific accounts provides a new perspective on the open problem of developing an account of knowledge-based decisions. Specifically, I argue that the biggest open problem regarding knowledge-based decisions is not how we respond to uncertainty, but rather how we assess the relevance of our many disparate pieces of knowledge, choosing which to integrate, and how. A strong case emerges for a procedural solution to this part of the problem of how to make knowledge-based decisions. (shrink)