Our brains make up a series of signs and are engaged in making or manifesting or reacting to a series of signs: through this semiotic activity they are at the same time engaged in “being minds.” An important effect of this semiotic activity of brains is a continuous process of “externalization of the mind” that exhibits a new cognitive perspective on the mechanisms underlying the semiotic emergence of abductive processes of meaning formation. I consider this process of externalization interplay critical (...) in analyzing the relation between meaningful semiotic internal resources and devices and their dynamical interactions with the externalized semiotic materiality suitably stocked in the environment. The last part of the paper will describe some aspects of this interplay between external diagrammatization and internal recapitulation showing the specificity of their co-evolution. (shrink)