I offer an explicit account of the underdetermination thesis as well as of the many challenges it poses to scientific realism; a way to answer to these challenges is explored and outlined, by shifting attention to the content of theories. I argue that, even if we have solid grounds (as I contend we do) to support that some varieties of the underdetermination thesis are true, scientific realism can still offer an adequate picture of the aims and achievements of science.

Mathematical concepts play at least three roles in the application of mathematics: an inferential role, a representational role, and an expressive role. In this paper, I argue that, despite what has often been alleged, platonists do not fully accommodate these features of the application of mathematics. At best, platonism provides partial ways of handling the issues. I then sketch an alternative, anti-realist account of the application of mathematics, and argue that this account manages to accommodate these features of the application (...) process. In this way, a better account of mathematical applications is, in principle, available. (shrink)

Newton da Costa and Steven French have argued that the concept of partial truth plays an important role in our understanding of significant aspects of scientific practice: from the status of scientific theories through the understanding of inconsistency in science to the nature of induction (see da Costa and French 2003). In this paper, I use the concept of partial truth and the associated framework of partial structures to offer a formulation of the concept of visual evidence, and I examine (...) some of the roles that this notion plays in scientific activity. DOI:10.5007/1808-1711.2011v15n2p249. (shrink)

This paper, which is based on recent empirical research at the University of Leeds, the University of Edinburgh, and the University of Bristol, presents two difficulties which arise when condensed matter physicists interact with molecular biologists: the former use models which appear to be too coarse-grained, approximate and/or idealized to serve a useful scientific purpose to the latter; and the latter have a rather narrower view of what counts as an experiment, particularly when it comes to computer simulations, than the (...) former. It argues that these findings are related; that computer simulations are considered to be undeserving of experimental status, by molecular biologists, precisely because of the idealizations and approximations that they involve. The complexity of biological systems is a key factor. The paper concludes by critically examining whether the new research programme of ‘systems biology’ offers a genuine alternative to the modelling strategies used by physicists. It argues that it does not. (shrink)