Hempel and Giere contend that the existence of provisos poses grave difficulties for any regularity account of physical law. However, Hempel and Giere rely upon a mistaken conception of the way in which statements acquire their content. By correcting this mistake, I remove the problem Hempel and Giere identify but reveal a different problem that provisos pose for a regularity account — indeed, for any account of physical law according to which the state of affairs described by a law-statement presupposes (...) a Humean regularity. These considerations suggest a normative analysis of law-statements. On this view, law-statements are not distinguished from accidental generalizations by the kind of Humean regularities they describe because a law-statement need not describe any Humean regularity. Rather, a law-statement says that in certain contexts, one ought to regard the assertion of a given type of claim, if made with justification, as a proper way to justify a claim of a certain other kind. (shrink)

Scientists use a variety of modes of representation in their work, but philosophers have studied mainly sentences expressing propositions. I ask whether diagrams are mere conveniences in expressing propositions or whether they are a distinct, ineliminable mode of representation in scientific texts. The case of path analysis, a statistical method for quantitatively assessing the relative degree of causal determination of variation as expressed in a causal path diagram, is discussed. Path analysis presents a worst case for arguments against eliminability since (...) path diagrams are usually presumed to be mathematically or logically “equivalent” in an important sense to sets of linear path equations. I argue that path diagrams are strongly generative, i.e., that they add analytical power to path analysis beyond what is supplied by linear equations, and therefore that they are ineliminable in a strong scientific sense. (shrink)

The paper provides a formal proof that efficient estimates of parameters, which vary as as little as possible when measurements are repeated, may be expected to provide more accurate predictions. The definition of predictive accuracy is motivated by the work of Akaike (1973). Surprisingly, the same explanation provides a novel solution for a well known problem for standard theories of scientific confirmation — the Ravens Paradox. This is significant in light of the fact that standard Bayesian analyses of the paradox (...) fail to account for the predictive utility of universal laws like All ravens are black. (shrink)

More laws obtain in the world,it appears, than just those of microphysics –e.g. laws of genetics, perceptual psychology,economics. This paper assumes there indeedare laws in the special sciences, and notjust scrambled versions of microphysical laws. Yet the objects which obey them are composedwholly of microparticles. How can themicroparticles in such an object lawfully domore than what is required of them by the lawsof microphysics? Are there additional laws formicroparticles – which seems to violate closureof microphysics – or is the ``more'' (...) acoincidental outcome of microphysics itself? This paper argues that the appearance ofviolation is illusory, and the worry aboutcoincidence misleading. We cannot expect tounderstand the special sciences at the level ofthe microparticles. (shrink)

In many applications of physics, boundary conditions have an essential role. The purpose of this paper is to examine from both a historical and philosophical perspective one such boundary condition, namely, the no-slip condition of fluid dynamics. The historical perspective is based on the works of George Stokes and serves as the foundation for the philosophical perspective. It is seen that historically the acceptance of the no-slip condition was problematic. Philosophically, the no-slip condition is interesting since the use of the (...) no-slip condition illustrates nicely the use of scientific models. But more importantly, both the use and justification of the no-slip condition illustrate clearly how theories can holistically approach the world through model construction. Further, since much of the debate over scientific realism occurs in the realm of models, a case is made that an understanding of the role of the no-slip condition has something to offer to this debate. (shrink)

There is a long history of controversy in ecology over the role of competition in determining patterns of distribution and abundance, and over the significance of the mathematical modeling of competitive interactions. This paper examines the controversy. Three kinds of considerations have been involved at one time or another during the history of this debate. There has been dispute about the kinds of regularities ecologists can expect to find, about the significance of evolutionary considerations for ecological inquiry, and about the (...) empirical credentials of theoretical studies of competition. Each of these elements is examined with an eye toward gaining philosophical clarification of the issues involved. In the process, certain shortcomings of contemporary philosophical theories are revealed. In particular, I argue that plausibility arguments based on background considerations are an important part of the model building tradition, but that current accounts of the structure and evaluation of scientific theories do little to illuminate this side of theoretical ecology. (shrink)

The theoretical system Lyell presented in 1830 was composed of three requirements or principles: 1) the Uniformity Principle which states that past geological events must be explained by the same causes now in operation; 2) the Uniformity of Rate Principle which states that geological laws operate with the same force as at present; 3) the Steady-state Principle which states that the earth does not undergo any directional change. The three principles form a single thesis called uniformitarianism which has been repeatedly (...) questioned and which has been reputed to be unable to face the competing directional synthesis based on the theory of the earth's cooling down. As a result, the significance of Lyell's system has been reduced to a simple actualism which admits the validity of the only Uniformity Principle. I believe that the only way to understand Lyell's role in the history of science is to maintain the unity of his synthesis. To show the Newtonian roots of this synthesis I will compare Lyell's principles and Newton's Rules of Reasoning. I will conclude with an analysis of the methodological function of principles in Lyell's scientific endeavour. (shrink)

All sides in the recent debates over the Quine‐Putnam Indispensability thesis presuppose Quine's criterion for determining what a discourse is ontologically committed to. I subject the criterion to scrutiny, especially in regard to the available competitor‐criteria, asking what means of evaluation there are for comparing alternative criteria against each other. Finding none, the paper concludes that ontological questions, in a certain sense, are philosophically indeterminate.

Jarrett Leplin in A Novel Defense of Scientific Realism (1997) argues that if the thesis of empirical equivalence is cogent, then the thesis of underdetermination cannot even get off the ground. Part of Leplin's argument rests on the claim that auxiliary hypotheses can be independently confirmed, thus enabling us to determine the epistemic worth of a theory. This, in turn, helps in determining about what we should be realists. Leplin's claims are demonstrated to be problematic. Leplin wants, inconsistently, to use (...) only those auxiliary hypotheses which dovetail with confirmed theories. Finally, a detail of Leplin's argument is found wanting. (shrink)

This paper is an attempt to further our understanding of mechanisms conceived of as ontologically separable from laws. What opportunities are there for a mechanistic perspective to be independent of, or even more fundamental than, a law perspective? Advocates of the mechanistic view often play with the possibility of internal and external reliability, or with the paralleling possibilities of enforcing, counteracting, redirecting, etc., the mechanisms’ power to produce To further this discussion I adopt a trope ontology. It is independent of (...) the notion of law, and can easily be adapted to account for such characteristics of mechanisms. The idea of tropes as mechanisms is worked out in some detail. According to the resulting picture, there is still an opportunity to link mechanisms and laws. But while the predominant law view conceives of mechanistic approaches as special kinds of law accounts, this study indicates that the converse may be true. Law accounts are special cases of mechanistic accounts, and they work only in those worlds where the mechanisms are of the right kind. (shrink)

This paper argues for two related theses. The first is that mathematical abstraction can play an important role in shaping the way we think about and hence understand certain phenomena, an enterprise that extends well beyond simply representing those phenomena for the purpose of calculating/predicting their behaviour. The second is that much of our contemporary understanding and interpretation of natural selection has resulted from the way it has been described in the context of statistics and mathematics. I argue for these (...) claims by tracing attempts to understand the basis of natural selection from its early formulation as a statistical theory to its later development by R.A. Fisher, one of the founders of modern population genetics. Not only did these developments put natural selection of a firm theoretical foundation but its mathematization changed the way it was understood as a biological process. Instead of simply clarifying its status, mathematical techniques were responsible for redefining or reconceptualising selection. As a corollary I show how a highly idealised mathematical law that seemingly fails to describe any concrete system can nevertheless contain a great deal of accurate information that can enhance our understanding far beyond simply predictive capabilities. (shrink)

One of Nancy Cartwright's arguments for entity realism focuses on the non-redundancy of causal explanation. In How the Laws of Physics Lie she uses an example from laser theory to illustrate how we can have a variety of theoretical treatments governing the same phenomena while allowing just one causal story. In the following I show that in the particular example Cartwright chooses causal explanation exhibits the same kind of redundancy present in theoretical explanation. In an attempt to salvage Cartwright's example (...) the causal explanation could be reinterpreted as a capacity claim, as outlined in her recent work Nature's Capacities and Their Measurement. However, I argue that capacities cannot be isolated in the way that Cartwright suggests and consequently these capacity claims also fail to provide a unique causal story. We can, however, make sense of capacities by characterizing them in a relational way and I offer some ideas as to how this approach would retain our intuitions about capacities while denying their ontological priority as dormant powers. (shrink)

has offered evidential decision theorists a defence against the charge that they make unintuitive recommendations for cases like Newcomb's Problem. He says that when conditional probabilities are assessed from the agent's point of view, evidential decision theory makes the same recommendation as intuition. I argue that calculating the probabilities in Price's way leads to no recommendation. It condemns the agent to perpetual oscillation between different options. Price's Argument Instability Objections Conclusion.

Nancy Cartwright argues that so-called capacities, not universal laws of nature, best explain the often complex way events actually unfold. On this view, science would represent a world that is fundamentally "dappled", or disunified, and not, as orthodoxy would perhaps have it, a world unified by universal laws of nature. I argue, first, that the problem Cartwright raises for laws of nature seems to arise for capacities too, so why reject laws of nature? Second, that in so far as there (...) is a problem, it concerns the role of counterfactuals in explanation; I then briefly propose a simple model of counterfactual explanation. Finally, I investigate how a sophisticated version of the regularity theory of laws of nature (that of Ramsey-Lewis) can be neutral between the empirical hypotheses that the world is unified, and that the world is disunified. (shrink)

Traditional analyses of the curve fitting problem maintain that the data do not indicate what form the fitted curve should take. Rather, this issue is said to be settled by prior probabilities, by simplicity, or by a background theory. In this paper, we describe a result due to Akaike [1973], which shows how the data can underwrite an inference concerning the curve's form based on an estimate of how predictively accurate it will be. We argue that this approach throws light (...) on the theoretical virtues of parsimoniousness, unification, and non ad hocness, on the dispute about Bayesianism, and on empiricism and scientific realism. * Both of us gratefully acknowledge support from the Graduate School at the University of Wisconsin-Madison, and NSF grant DIR-8822278 (M.F.) and NSF grant SBE-9212294 (E.S.). Special thanks go to A. W. F. Edwards.William Harper. Martin Leckey. Brian Skyrms, and especially Peter Turney for helpful comments on an earlier draft. (shrink)

The overarching aim of this essay is to argue that moral realists should be "causalists" or claim that moral facts of certain kinds are causally efficacious. To this end, I engage in two tasks. The first is to develop an account of the sense in which moral facts of certain kinds are causally efficacious. After having sketched the concept of what I call a "configuring" cause, I contend that the exercise of the moral virtues is plausibly viewed as a configuring (...) cause. The second is to show that the causalist position I develop can withstand objections inspired by the work of Robert Audi and Jaegwon Kim. (shrink)

Using Jim Woodward's Counterfactual Dependency account as an example, I argue that causal claims about indeterministic systems cannot be satisfactorily analysed as including counterfactual conditionals among their truth conditions because the counterfactuals such accounts must appeal to need not have truth values. Where this happens, counterfactual analyses transform true causal claims into expressions which are not true.

This paper deals with the problem of derivational redundancy in scientific explanation, i.e. the problem that there can be extremely many different explanatory derivations for a natural phenomenon while students and experts mostly come up with one and the same derivation for a phenomenon (modulo the order of applying laws). Given this agreement among humans, we need to have a story of how to select from the space of possible derivations of a phenomenon the derivation that humans come up with. (...) In this paper we argue that the problem of derivational redundancy can be solved by a new notion of “shortest derivation”, by which we mean the derivation that can be constructed by the fewest (and therefore largest) partial derivations of previously derived phenomena that function as “exemplars”. We show how the exemplar-based framework known as “Data-Oriented Parsing” or “DOP” can be employed to select the shortest derivation in scientific explanation. DOP’s shortest derivation of a phenomenon maximizes what is called the “derivational similarity” between a phenomenon and a corpus of exemplars. A preliminary investigation with exemplars from classical and fluid mechanics shows that the shortest derivation closely corresponds to the derivations that humans construct. Our approach also proposes a concrete solution to Kuhn’s problem of how we know on which exemplar a phenomenon can be modeled. We argue that humans model a phenomenon on the exemplar that is derivationally most similar to the phenomenon, i.e. the exemplar from which the largest subtree(s) can be used to derive the phenomenon. (shrink)

The characteristic difference between laws and accidental generalizations lies in our epistemic or inductive attitude towards them. This idea has taken various forms and dominated the discussion about lawlikeness in the last decades. Likewise, the issue about ceteris paribus conditions is essentially about how we epistemically deal with exceptions. Hence, ranking theory with its resources of defeasible reasoning seems ideally suited to explicate these points in a formal way. This is what the paper attempts to do. Thus it will turn (...) out that a law is simply the deterministic analogue of a sequence of independent, identically distributed random variables. This entails that de Finetti's representation theorems can be directly transformed into an account of confirmation of laws thus conceived. (shrink)

Unentwegt werden neue technische Produkte gestaltet. Doch was macht die technische Gestaltung aus? Wie lässt sich ihr Gegenstand - (noch) nicht existierende Artefakte - adäquat auf den Begriff bringen? Michael Kuhn begreift technische Ideen vor ihrer Realisierung als Fiktionen. Er bietet eine fiktionstheoretische Rekonstruktion der Gestaltungstätigkeit und entwickelt hieraus eine Ethik der Gestaltung. Der stark interdisziplinäre Zugang zwischen Technikphilosophie und Ingenieurwissenschaften liefert neue Erkenntnisse für beide Fachrichtungen und stellt wertvolle Grundlagen bereit.

The word “effective” has become the standard label attached to scientific theories these days. An effective theory allows us to make accurate predictions about a physical system at a certain (energy, length) scale while being largely ignorant of the details at more fundamental levels. One does not need to know anything about the deeper, quantum structure of water molecules to describe the macroscopic behaviour of waves or water in a glass. Although effective descriptions so broadly construed have been part of (...) research in physics since the earliest stages of modern science, it is particle physics that has most clearly relied on and brought to the fore some of the most interesting and admittedly puzzling aspects of this way of looking at theories. Indeed, the effective field theory (EFT) program in QFT has established itself as the most natural way to understand renormalisation and dissipate initial reservations about the status of these techniques by treating higher-order processes as contributions suppressed at lower energy scales. QFT is thus treated as the “effective” framework par excellence with the decoupling of scales constituting its permeating tenet. The goal of this project is to attempt a philosophical appraisal of EFTs as currently used in high energy physics as well as assess the possibility that the whole program eventually breaks down, i.e. fails to apply when certain preconditions do not hold. Accordingly, the dissertation is logically divided into two parts with the first two chapters dedicated to discussion of the relation between EFTs and traditional questions in the philosophy of science concerning the structure of scientific theories, the formulation and defence of scientific realism as well as its connection to possible ontological readings of EFTs. The second part constitutes an analysis of two well-known problems that have been accorded the status of crises in the physics literature: the hierarchy problem and the cosmological constant problem. Our main focus will be to uncover those assumptions responsible for undermining the validity of the EFT techniques in their respective context. In light of this analysis, we will ultimately lean towards a more cautionary or “reserved” approach to EFTs. (shrink)

It seems to be a platitude that there must be a close connection between causality and the laws of nature: the laws somehow cover in general what happens in each specific case of causation. But so-called singularists disagree, and it is often thought that the locus classicus for that kind of dissent is Anscombe's famous Causality & Determination. Moreover, it is often thought that Anscombe's rejection of determinism is premised on singularism. In this paper, I show that this is a (...) mistake: Anscombe is not a singularist, but in fact only objects to a very specific, Humean understanding of the generality of laws of nature and their importance to causality. I argue that Anscombe provides us with the contours of a radically different understanding of the generality of the laws, which I suggest can be fruitfully developed in terms of recently popular dispositional accounts. And as I will show, it is this account of laws of nature (and not singularism) that allows for the possibility of indeterminism. (shrink)

Philosophy Compass, Volume 17, Issue 1, January 2022.

Um dos grandes desafios da era da informação consiste em filtrar informações claras, rigorosas e atualizadas sobre tópicos importantes. O mesmo vale para a filosofia. Como encontrar conteúdo filosófico confiável em meio a milhares de artigos publicados diariamente na internet? Para ir ainda mais longe, como encontrar uma introdução a algum tópico com uma lista de referências bibliográficas atualizadas e que seja organizada por um especialista da área? Já que você começou a ler este livro, é provável que tenha ouvido (...) falar em algum momento da Enciclopédia Stanford de Filosofia, disponível gratuitamente na internet desde 1995. A página da Stanford faz exatamente isso. Ela cobre inúmeros verbetes sobre quase tudo em filosofia, oferecendo informação confiável sobre temas como feminismo, filosofia na América Latina, zumbis, metafísica e milhares de outros tópicos. A sugestão típica aos profissionais da filosofia que têm interesse em começar a estudar algum tópico, mas não sabem sequer por onde começar, é procurar pelo verbete relevante da Stanford. Infelizmente, o grande empecilho da página para o nosso contexto é que todos os verbetes estão disponíveis apenas em inglês, algo que cria um obstáculo a inúmeros estudantes e interessados que não dominam a língua. Neste sentido, acreditamos que esta publicação preencha um hiato importante na filosofia brasileira. Embora a filosofia no Brasil tenha se profissionalizado e expandido ao longo dos anos, há ainda lacunas em diversas áreas, e os verbetes foram aqui selecionados cuidadosamente no intuito de preencher ao menos algumas dessas lacunas. Este livro apresenta quatro verbetes cruciais para a filosofia, aqui divididos em quatro capítulos: (1) condições necessárias e suficientes, (2) referência (3) causação e (4) consciência. (shrink)

Do causes necessitate their effects? Causal necessitarianism is the view that they do. One major objection—the “monotonicity objection”—runs roughly as follows. For many particular causal relations, we can easily find a possible “blocker”—an additional causal factor that, had it also been there, would have prevented the cause from producing its effect. However—the objection goes on—, if the cause really necessitated its effect in the first place, it would have produced it anyway—despite the blocker. Thus, CN must be false. Though different (...) from Hume’s famous attacks against CN, the monotonicity objection is no less important. In one form or another, it has actually been invoked by various opponents to CN, past and present. And indeed, its intuitive appeal is quite powerful. Yet, this paper argues that, once carefully analysed, the objection can be resisted—and should be. First, I show how its success depends on three implicit assumptions concerning, respectively, the notion of cause, the composition of causal factors, and the relation of necessitation. Second, I present general motivations for rejecting at least one of those assumptions: appropriate variants of them threaten views that even opponents to CN would want to preserve—in particular, the popular thesis of grounding necessitarianism. Finally, I argue that the assumption we should reject is the one concerning how causes should be understood: causes, I suggest, include an element of completeness that excludes blockers. In particular, I propose a way of understanding causal completeness that avoids common difficulties. (shrink)

"Partial realism" is a common position in the contemporary philosophy of science literature. It states that the "essential" elements of empirically successful scientific theories accurately represent corresponding features the world. This thesis makes several novel contributions related to this position. Firstly, it offers a new definition of the concept of “empirical success”, representing a principled merger between the use-novelty and unification accounts. Secondly, it provides a comparative critical analysis of various accounts of which elements are "essential" to the success of (...) a theory, including structural realism and the divide et impera strategy. A novel account of essentialness, entitled the “empirically successful sub-theory "account", is defended. Thirdly, it is argued that the realism/anti-realism debate should put to the side metaphysical questions and focus instead on partial realism's commitment to the continuity of science. Because this commitment lacks metaphysical implications, it is referred to as "deflationary realism". Anti-realists cannot reject deflationary realism as a matter of a priori principle; its overall viability can therefore only be assessed by a careful examination of the history of science. Finally, another consequence of partial realism, named "partial rationalism", is defended. Partial rationalism states that, in cases where several competing theories have been suggested, scientists are rational just in case they accept the essential elements of each of the scientific theories on offer. This novel position subverts the existing literature on scientific "revolutions", as it sometimes demands that scientists devise a synthesis between competing scientific theories, instead of "choosing" only one. The philosophical points defended in this thesis are illustrated and supported by case studies from the history of science, including Fresnel’s wave theory of light, the Copernican revolution, the "neo-Darwinian synthesis" in evolutionary biology, the "prion revolution" in molecular biology, the miasma theory of disease, and the chemical revolution. (shrink)

Quantum Mechanics has faced deep controversies and debates since its origin when Werner Heisenberg proposed the first mathematical formalism capable to operationally account for what had been recently discovered as the new field of quantum phenomena. Today, even though we have reached a standardized version of QM which is taught in Universities all around the world, there is still no consensus regarding the conceptual reference of the theory and, if or if not, it can refer to something beyond measurement outcomes. (...) In this work we will argue that the reason behind the impossibility to reach a meaningful answer to this question is strictly related to the 20th Century Bohrian-positivist re-foundation of physics which is responsible for having introduced within the theory of quanta a harmful combination of metaphysical dogmatism and naive empiricism. We will also argue that the possibility of understanding QM is at plain sight, given we return to the original framework of physics in which the meaning of understanding has always been clear. (shrink)

Multiple determination is the epistemic strategy of establishing the same result by means of multiple, independent procedures. It is an important strategy praised by both philosophers of science and practicing scientists. Despite the heavy appeal to multiple determination, little analysis has been provided regarding the specific grounds upon which its epistemic virtues rest. This article distinguishes between the various dimensions of multiple determination and shows how they can be used to evaluate the epistemic force of the strategy in particular cases. (...) Distinguishing between the various dimensions helps to resolve the disagreements regarding the relevance and epistemic import of multiple determination for scientific research. It also suggests a fruitful mode of interaction between the philosophy of science and (historical) accounts of scientific practice. (shrink)

The paper deals with the philosophy of science and technology from a new perspective. The analysis connects closely to the novel approach to scientific research called practical realism of the late Estonian philosopher of science and chemistry Rein Vihalemm. From his perspective, science is not only theoretical but even more clearly a practical activity. This kind of practice-based approach puts chemistry rather than physics into the position of the most typical science as chemistry has a dual character resting on both (...) constructive-hypothetico-deductive and classifying-historico-descriptive types of cognition. Chemists deal with finding out the laws of nature just like the physicists do. However, in addition to this chemistry deals with substances or stuff that is rather an activity typical to natural history. The analysis of the dual character of chemistry brings forward the need to analyse philosophically also the reasons why physics has held the position of the model science so far. The problem unfolds in the context of practical realism. However, some earlier observations concerning the dual character of chemistry influenced us as well, i.e. by Friedrich Paneth, Michael Polanyi and Edward Caldin. More recently, Bernadette Bensaude-Vincent and Jonathan Simon have given their own explanation of why and how chemistry has a dual character. From their perspective, chemistry is a perfect technical science as it aims at applications, literally at producing something new. Bensaude-Vincent and Simon call their approach operational realism. The latter, however, does not differ from practical realism. (shrink)

Science is replete with falsehoods that epistemically facilitate understanding by virtue of being the very falsehoods they are. In view of this puzzling fact, some have relaxed the truth requirement on understanding. I offer a factive view of understanding that fully accommodates the puzzling fact in four steps: (i) I argue that the question how these falsehoods are related to the phenomenon to be understood and the question how they figure into the content of understanding it are independent. (ii) I (...) argue that the falsehoods do not figure into the understanding’s content by being elements of its periphery or core. (iii) Drawing lessons from case studies, I argue that the falsehoods merely enable understanding. When working with such falsehoods, only the truths we extract from them are elements of the content of our understanding. (iv) I argue that the extraction view is compatible with the thesis that falsehoods can have an epistemic value by virtue of being the very falsehoods they are. (shrink)

The aim of this paper is to explore the possibility that, at least, some metaphysical debates are ‘metalinguistic negotiations’. I will take the dispute between the dominant approaches of realism and the anti-realism ones about the ontological status of scientific models as a case-study. I will argue that such a debate may be better understood as a disagreement, at bottom normatively, motivated, insofar as a normative and non-factual question may be involved in it: how the relevant piece of language ought (...) to be used. Even though I will generally assess the prospects for a broadly deflationist approach, I shall outline a sense in which the dispute can be recast as ‘minimally substantive’. (shrink)

This study considers the short list of Nature of Science features frequently published and widely known in the science education discourse. It is argued that these features were oversimplified and a refinement of the claims may enrich or sometimes reverse them. The analysis shows the need to address the range of variation in each particular aspect of NOS and to illustrate these variations with actual events from the history of science in order to adequately present the subject. Another implication of (...) the proposal is the highlighting of the central role of science educators who, facing various strong claims of researchers in education and philosophy of science, often have difficulty in making a choice of what to teach about NOS. It is suggested that a representative variation with regard to the traditional NOS claims may be appropriate for a genuine understanding of the subject. In that, using the discipline-culture structure of the fundamental theories of physics and addressing the plurality of scientific methods may be helpful in the actual teaching and learning of NOS. (shrink)

Personalised medicine has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells so as to make individualised treatment predictions. We compare this strategy to two main PM strategies—stratified medicine and (...) computational models. Drawing on epistemological work in the philosophy of medicine, we explain why these two methods, while powerful, are neither truly personalised nor, epistemologically speaking, novel strategies. Both are forms of correlational black box. We then argue that the iPSC models would count as a new kind of black box. They would not rely entirely on mechanistic knowledge, and they would utilise correlational evidence in a different way from other strategies—a way that would enable personalised predictions. In arguing that the iPSC models would present a novel method of gaining evidence for clinical practice, we provide an epistemic analysis that can help to inform the practical, regulatory, and ethical challenges of developing an iPSC system. (shrink)

String theory has not even come close to a complete formulation after half a century of intense research. On the other hand, a number of features of the theory suggest that the theory, once completed, may be a final theory. It is argued in this chapter that those two conspicuous characteristics of string physics are related to each other. What links them together is the fact that string theory has no dimensionless free parameters at a fundamental level. The paper analyses (...) possible implications of this situation for the long term prospects of theory building in fundamental physics. (shrink)

Positivism has been used to establish a standard that Information Systems (IS) research must meet to be scientific. According to such positivistic beliefs in IS, scientific research should: 1) be generalizable, 2) focus on stable independent variables, 3) have certain ontological assumptions, and 4) use statistical or quantitative methods rather than qualitative methods. We argue that logical positivist philosophers required none of these. On the contrary, logical positivist philosophers regarded philosophizing in general and ontological considerations in particular as nonsense. Moreover, (...) the positivists’ preferred empirical research method was not a survey, but rather a qualitative observation recorded by field notes. In addition, positivist philosophers required neither statistical nor nonstatistical generalizability. At least some positivist philosophers also acknowledged the study of singular cases as being scientific. Many research orientations (e.g., single-setting research, examination of change, qualitative research) that are deemed “unscientific” by positivism in IS seem to be “scientific” (in principle) according to logical positivism. In turn, generally speaking, what has been justified as scientific by positivism in IS (e.g., requirements of statistical or nonstatistical generalizability, surveys, independent variables, ontological views) were either not required by logical positivists or were regarded as nonsensical by logical positivists. Furthermore, given that positivism is sometimes associated (or confused) with logical empiricism in IS, we also briefly discuss logical empiricism. Finally, realizing that certain influential, taken-forgranted assumptions that underlie IS research are unwarranted could have ground-breaking implications for future IS research. (shrink)

The paper discusses major implications of high energy physics for the scientific realism debate. The first part analyses the ways in which aspects of the empirically well-confirmed standard model of particle physics are relevant for a reassessment of entity realism, ontological realism and structural realism. The second part looks at the implications of more far-reaching concepts like string theory. While those theories have not found empirical confirmation, if they turned out viable, their implications for the realism debate would be more (...) substantial than those of the standard model. (shrink)

Understanding Nature of Science is a central component of scientific literacy, which is agreed upon internationally, and consequently has been a major educational goal for many years all over the globe. In order to justify the promotion of an adequate understanding of NOS, educators have developed several arguments, among them the cultural argument. But what is behind this argument? In order to answer this question, C. P. Snow’s vision of two cultures was used as a starting point. In his famous (...) Rede Lecture from 1959, he complained about a wide gap between the arts and humanities on the one hand and sciences on the other hand. While the representatives of the humanities refer to themselves as real intellectuals, the scientists felt rather ignored as a culture, despite the fact that their achievements had been so important for Western society. Thus, Snow argued that as these intellectual cultures were completely different from each other, a mutual understanding was impossible. The first European Regional IHPST Conference took up the cultural view on science again. Thus, the topic of the conference “Science as Culture in the European Context” encouraged us to look at the two cultures and to figure out possibilities to bridge the gap between them in chemistry teacher education. For this reason, we put together three studies—one theoretical and two independent research projects which contribute to our main research field —in order to address the cultural argument for understanding science from an educational point of view. Among the consented tenets of what understanding NOS implies in an educational context, there are aspects which are associated mainly with the humanities, like the tentativeness of knowledge, creativity, and social tradition, whereas others seem to have a domain-specific meaning, like empirical evidence, theories and laws, and the role of technology. Thus, the cultural argument for understanding science invites us not only to consider domain-specific concepts but also to reflect on similarities between science and the humanities by way of examples. (shrink)

Scientific reasoning is particularly pertinent to science education since it is closely related to the content and methodologies of science and contributes to scientific literacy. Much of the research in science education investigates the appropriate framework and teaching methods and tools needed to promote students’ ability to reason and evaluate in a scientific way. This paper aims to contribute to an extended understanding of the nature and pedagogical importance of model-based reasoning and to exemplify how using computer simulations can support (...) students’ model-based reasoning. We provide first a background for both scientific reasoning and computer simulations, based on the relevant philosophical views and the related educational discussion. This background suggests that the model-based framework provides an epistemologically valid and pedagogically appropriate basis for teaching scientific reasoning and for helping students develop sounder reasoning and decision-taking abilities and explains how using computer simulations can foster these abilities. We then provide some examples illustrating the use of computer simulations to support model-based reasoning and evaluation activities in the classroom. The examples reflect the procedure and criteria for evaluating models in science and demonstrate the educational advantages of their application in classroom reasoning activities. (shrink)

ABSTRACTThis article responds to McWherter’s detailed critique of my assessment of Roy Bhaskar’s method of transcendental argumentation in chapter four of my Naturalizing Critical Realist Social Ontology. I begin by describing some naturalist ontological and epistemological views defended in my book, thereby showing that my naturalist challenge to the original version of critical realism is not only methodological but also substantial. I also indicate that this point is effectively downplayed in McWherter’s framing of the debate in terms of competing metaphilosophies. (...) I then consider how the doctrine of transcendental idealism is presupposed in Kant’s transcendental deduction and question the consistency of McWherter’s various descriptions of Bhaskar’s transcendental arguments. Finally, I provide detailed responses to McWherter’s objectives to my views. My conclusion is that naturalized critical realism is a more coherent and scientifically viable position than the neo-Kantian version of critical realism defended by McWherter. Nevertheless, I think that there is enough overlap between original and naturalized critical realism to regard the latter as a revised and elaborated version of the former. (shrink)

Stephen Yablo has recently argued for a novel solution to the mental causation problem: the mental is related to the physical as determinables are related to determinates; determinables are not causal rivals with their determinates; so the mental and the physical are not causal rivals. Despite its attractions the suggestion seems hard to accept. In this paper I develop the idea that mental properties and physical properties are not causal rivals. Start with property dualism, supervenience, multiple realizability, and the claim (...) that no more than one supervenience base for a mental property can be had by a single instance of the mental property. Then a probabilistic account of causation will be unable to certify either mental properties or physical properties as causal factors for effect types. I suggest that this shows that we should not count mental properties as causal rivals with physical properties. (shrink)

During the past decades several philosophers of science and social scientists have been interested in the problems of causation. Recently attention has been given to probabilistic causation in dichotomous causal systems. The paper uses the basic features of probabilistic causation to argue that the causal modeling approaches developed by such researchers as Blalock and Duncan can provide, when an additional assumption is added, adequate qualitative measures of one variableś causal influence upon another. Finally, some of the difficulties and issues involved (...) in developing adequate quantitative measures are discussed, and it is concluded that the causal modeling measures cannot provide adequate quantitative measures. (shrink)

Various traditions in mental health care, such as phenomenological, and existential and cognitive-behavioral psychotherapy, implicitly or explicitly acknowledge that a disruption of the self, or the person, or the agent is among the common denominators of different mental disorders. They often emphasize the importance of understanding patients as reasonsresponsive, in their full mental health relevant complexity, if their mental disorder is to be treated successfully. The centrality of the concept of the self is not mirrored in the mainstream scientific approaches (...) in psychiatry however; the self has rarely been considered as the object of scientific research, the empirical investigation of which might yield successful explanations of and interventions in mental disorders. Thus, even though self-related phenomena are clinically relevant in so far as they give important information about a mental disorder to the clinician and help the development of effective interventions, they are not considered among the scientifically relevant properties of mental disorders. Leaving the self-related phenomena out of the scientific research on mental disorders can be attributed to the presupposition that the self is not empirically tractable and its use will hinder psychiatry’s goal to be scientific. In this paper, taking issue with this, I argue the self is empirically tractable, and its use as a target of research will not hinder psychiatry’s scientific commitments. (shrink)