This work addresses biological explanations and aims to provide a philosophical account which brings together logical-procedural and historical-processual aspects when considering molecular pathways. It is argued that, having molecular features as explananda, a particular non-classical logical language – Zsyntax – can be used to formally represent, in terms of logical theorems, types of molecular processes, and to grasp how we get from one molecular interaction to another, hence explaining why a given outcome occurs. Expressing types of molecular biology processes in (...) terms of the Zsyntax language allows us to represent causal interactions by taking into account their context-sensitivity, and amounts to partly reviving the spirit of the so-called received view of explanation – which aimed to capture scientific explanatory accounts in terms of their logical structure and their appealing to nomological relations. Such a partial revival is pursued by invoking here non-classical deductions and empirical generalisations, which are called to provide the epistemic norms to explain the behavior of molecular pathways. (shrink)

Abductive reasoning involves finding the missing premise of an “unsaturated” deductive inference, thereby selecting a possible _explanans_ for a conclusion based on a set of previously accepted premises. In this paper, we explore abductive reasoning from a structural proof-theory perspective. We present a hybrid sequent calculus for classical propositional logic that uses sequents and antisequents to define a procedure for identifying the set of analytic hypotheses that a rational agent would be expected to select as _explanans_ when presented with an (...) abductive problem. Specifically, we show that this set may not include the deductively minimal hypothesis due to the presence of redundant information. We also establish that the set of all analytic hypotheses exhausts all possible solutions to the given problem. Finally, we propose a deductive criterion for differentiating between the best _explanans_ candidates and other hypotheses. (shrink)

Some real life processes, including molecular ones, are context-sensitive, in the sense that their outcome depends on side conditions that are most of the times difficult, or impossible, to express fully in advance. In this paper, we survey and discuss a logical account of context-sensitiveness in molecular processes, based on a kind of non-classical logic. This account also allows us to revisit the relationship between logic and philosophy of science (and philosophy of biology, in particular).