A recent study by Castellani et al. (JAMA 302(23):2573–2579, 2009) describes the population-level effects of the choices of individuals who underwent molecular carrier screening for cystic fibrosis (CF) in Veneto, in the northeastern part of Italy, between 1993 and 2007. We discuss some of the ethical issues raised by the policies and individual choices that are the subject of this study. In particular, (1) we discuss the ethical issues raised by the acquisition of genetic information through antenatal carrier testing; (2) (...) we consider whether by choosing to procreate naturally these couples can harm the resulting child and/or other members of society, and what the moral implications of such harm would be; (3) we consider whether by choosing to avoid natural procreation carrier couples can harm current or future individuals affected by cystic fibrosis; (4) we discuss whether programs that make carrier testing available can be considered eugenic programs. (shrink)

Ethical concerns in e-social science are often raised with respect to privacy, confidentiality, anonymity and the ethical and legal requirements that govern research. In this article, the authors focus on ethical aspects of e-research that are not directly related to ethical regulatory framework or requirements. These frameworks are often couched in terms of benefits or harms that can be incurred by participants in the research. The authors shift the focus to the sources of value in terms of which benefits or (...) harms are understood in real social situations. A central claim of this paper is that the technologies that are used for research are not value neutral, but serve to reinforce some values at the expense of others. The authors discuss databases, modelling and simulation, network analysis as examples of technologies which affect the articulation of values. A view of e-social science as a techno-scientific constellation of researchers, technologies and society, in which values are always already embedded, is put forward as a basis for a view of ethics as reflexive and active engagement, conducted with awareness. Methodological pluralism and proactive openness are also proposed as responses to this view of the ethical dimensions of e-social science. (shrink)

Based on Pritchard’s distinction (2012, 2016) between favoring and discriminating epistemic grounds, and on how those grounds bear on the elimination of skeptical possibilities, I present the dream argument as a moderate skeptical possibility that can be reasonably motivated. In order to block the dream argument skeptical conclusion, I present a version of phenomenological disjunctivism based on Noë’s actionist account of perceptual consciousness (2012). This suggests that perceptual knowledge is rationally grounded because it is a form of embodied achievement – (...) what I call embodied rationality –, which offers a way of dissolving the pseudo-problem of epistemic immodesty, namely, the seemingly counterintuitive thesis that one can acquire rationally grounded knowledge that one is not in a radical skeptical scenario. (shrink)

This work is about the philosophical aspects of Giovanni Urbani‟s thought, that is those reflections which constantly refer to Martin Heidegger‟s philosophy. The interest in these theoretical aspects doesn‟t stem from the necessity to determine whether Urbani has correctly understood the heideggerian lectio, but rather from a necessity of thought; the necessity to explain, in an originary way, how that particular kind of knowledge that develops through the experience of conservation is able to enrich and make speculative activity more (...) fruitful. Urbani‟s research, indeed, seems to find answers where the philosopher‟s thought stops, drifting toward mysticism. Thus the present work underlines the peculiar and original way Urbani understands Heidegger‟s lesson, starting just from the point where the theoretical aspects of their reflections start to diverge, and the idea that the conditions to build a new man and a new model of rationality are to be found within science substitutes the heideggerian waiting for the new coming of the Sacred, which is to happen in poetry: the knowledge and experience of conservation become the testing ground of this research, to which the duty to produce an «advance in civilization» has been entrusted. (shrink)

The paper introduces Vailati’s life and works, investigating Vailati’s education, the relation to Peano and his school, and the interest for pragmatism and modernism. A detailed analysis of Vailati’s scientific and didactic activities, shows that he held, like Peano, a a strong interest for the history of science and a pluralist, anti-dogmatic and anti-foundationalist conception of definitions in mathematics, logic and philosophy of language. Vailati’s understanding of mathematical logic as a form of pragmatism is not a faithful interpretation of Peano’s (...) conception, but it is essential to understand the relations of Peano’s logic with other philosophical traditions and some epistemological aspects of Peano’s perspective, such as the search for a universal language. (shrink)

The paper explores the original reception of Nietzsche's philosophy provided by the Italian pragmatists Giovanni Vailati and Giovanni Papini.

This is the review (in Polish) of G. Reale, History of ancient Philosophy, vol. II.

Giovanni Mion defends the idea that knowledge is context relative, but, in contrast to current versions of epistemic contextualism, on his view, knowledge is relative to contexts that are objective. Following Christopher Gauker’s conception of what a context is, Mion argues that knowledge is relative to the speakers’ conversational goals; and since the best way to achieve the goals of a conversation depends upon the way the world really is, it follows that participants in a conversation might be unaware (...) of the content of the context that truly governs their conversation. Finally, Mion uses objective contexts to explain why practical interests have epistemic significance. According to him, if we assume that the primary function of language is not to share thoughts, but to achieve practical goals, and, accordingly, that knowledge attributions play primarily an action-guiding role (as opposed to a mind-revealing role), then we are in a better position to understand why knowledge is not just a matter of theoretical factors, but it is also a matter of how much is at stake. (shrink)

Nel suo "Il canone minore", Rocco Ronchi descrive il tentativo compiuto da quelle figure, sovente eretiche del pensiero rispetto a quello che l’autore individua come canone maggiore, che nel corso della storia della filosofia hanno pensato davvero l'immanenza dell’assoluto o, che è lo stesso, l’univocità dell’essere sul piano degli enti di natura. Nell’esigenza fondamentalmente speculativa e per ciò stesso anti-moderna della filosofia, ciò che si dà a vedere quale dato immediato dell’intuizione è un'equivalenza solo apparentemente innocua, ma in realtà profondamente (...) perturbante e traumatica: immanenza assoluta = natura. (shrink)

Alexander Pope's An Essay on Man is part of a long tradition of meditating on the human person. In this review the antecedents of Modernism are revised and the Pope's Essay is reinstated as a tour de force which is all the more pertinent today.

This paper seeks to explore the way Giovanni Pico della Mirandola treated the Orphics and the Pythagoreans in his Conclusiones nongentae, his early and most ambitious work, so that he formulates his own philosophy. I do not intend to present and analyze the sum of Pico’s references to Orphics and Pythagoreans, since such an attempt is beyond the scope of this paper. Rather, I aim to highlight certain Pico’s aphorisms that allow readers to understand and evaluate his syncretic method (...) and his goals. In addition, I attempt to trace Pico’s sources and evaluate his proper knowledge, understanding and treatment of the Orphics and the Pythagoreans. Pico resorts to the Orphics and the Pythagoreans because he wants to give a practical and applied dimension to his philosophy. He attempted the revival of the original wisdom that underlies the traditions he combined. He was not a fan of the Aristotelian θεωρίης ἢνεκεν. Philosophy does not aim at proper knowledge, but is the key for the manipulation of the cosmos, physically and metaphysically speaking. Pico probably thinks of himself as the modern Orpheus: he does not intend to reveal the paths which cross the sensible and the intelligible, but he aspires to tread them. (shrink)

Information is a central notion for cognitive sciences and neurosciences, but there is no agreement on what it means for a cognitive system to acquire information about its surroundings. In this paper, we approximate three influential views on information: the one at play in ecological psychology, which is sometimes called information for action; the notion of information as covariance as developed by some enactivists, and the idea of information as minimization of uncertainty as presented by Shannon. Our main thesis is (...) that information for action can be construed as covariant information, and that learning to perceive covariant information is a matter of minimizing uncertainty through skilled performance. We argue that the agent’s cognitive system conveys information for acting in an environment by minimizing uncertainty about how to achieve her intended goals in that environment. We conclude by reviewing empirical findings that support our view and by showing how direct learning, seen as instance of ecological rationality at work, is how mere possibilities for action are turned into embodied know-how. Finally, we indicate the affinity between direct learning and sense-making activity. (shrink)

Solving the meta-problem of consciousness requires, among other things, explaining why we are so reluctant to endorse various forms of illusionism about the phenomenal. I will try to tackle this task in two steps. The first consists in clarifying how the concept of consciousness precludes the possibility of any distinction between 'appearance' and 'reality'. The second consists in spelling out our reasons for recognizing the existence of something that satisfies that concept.

Enactivism is a family of theories that construe action as constitutive of cognition and reject the need to postulate representations in order to explain all cognitive activities. Acknowledging a biologically basic, non-representational mode of cognition, however, raises the question of how to explain higher or more complex cognitive acts, what we call explanatory integration challenge. In this paper, we critically discuss some attempts to meet that challenge through scaling up basic cognition and through scaling down complex cognition within the enactivist (...) research program. (shrink)

The paper uses two historical examples, public health (1840-1880) and town planning (1945-1975) in Britain, to analyse the challenges faced by goal-driven research, an increasingly important trend in science policy, as exemplified by the prominence of calls for addressing Grand Challenges. Two key points are argued. (1) Given that the aim of research addressing social or global problems is to contribute to improving things, this research should include all the steps necessary to bring science and technology to fruition. This need (...) is captured by the idea of practical integration, which brings this type of research under the umbrella of collective practical reason rather than under the aegis of science. Achieving practical integration is difficult for many reasons: the complexity of social needs, the plurality of values at stake, the limitation of our knowledge, the elusive nature of the skills needed to deal with uncertainty, incomplete information and asymmetries of power. Nevertheless, drawing from the lessons of the case studies, it is argued that (2) practical integration needs a proper balance between values, institutions and knowledge: i.e. a combination of mutual support and mutual limitation. Pursuing such a balance provides a flexible strategy for approximating practical integration. (shrink)

This collection addresses two different audiences: 1) historians and philosophers of the life sciences reflecting on collaborations across disciplines, especially as regards defining and addressing Grand Challenges; 2) researchers and other stakeholders involved in cross-disciplinary collaborations aimed at tackling Grand Challenges in the life and medical sciences. The essays collected here offer ideas and resources both for the study and for the practice of goal-driven cross-disciplinary research in the life and medical sciences. We organise this introduction in three sections. The (...) first section provides some background and context. The second motivates our take on this topic and then outlines the central ideas of each paper. The third section highlights the specificity and significance of this approach by considering: a) how this collection departs from existing literature on inter- and trans-disciplinarity, b) what is characteristic about this approach, and c) what role this suggests for the history and philosophy of the life sciences in addressing Grand Challenges. (shrink)

This paper defends the view that one's own mental states are metaphysically privileged vis-à-vis the mental states of others, even if only subjectively so. This is an instance of a more general view called Subjectivism, according to which reality is only subjectively the way it is. After characterizing Subjectivism in analogy to two relatively familiar views in the metaphysics of modality and time, I compare the Subjectivist View of the Mental with Egocentric Presentism, a version of Subjectivism recently advocated by (...) Caspar Hare. I argue that the Subjectivist View of the Mental goes a considerable way towards solving certain long-standing philosophical puzzles having to do with the unity of consciousness, the contents of self-awareness and the intransmissibility of experiential knowledge through testimony. (shrink)

Many philosophers have been attracted to the idea of using the logical form of a true sentence as a guide to the metaphysical grounds of the fact stated by that sentence. This paper looks at a particular instance of that idea: the widely accepted principle that disjunctions are grounded in their true disjuncts. I will argue that an unrestricted version of this principle has several problematic consequences and that it’s not obvious how the principle might be restricted in order to (...) avoid them. My suggestion is that, instead of trying to restrict the principle, we should distinguish between metaphysical and conceptual grounds and take the principle to apply exclusively to the latter. This suggestion, if correct, carries over to other prominent attempts at using logical form as a guide to ground. (shrink)

The aims of my paper are to set out Aquinas’s arguments in favour of the thesis of God as Subsistent Being itself; set out the arguments against; and propose a fresh reading of that thesis that takes into account both Thomistic doctrine and the criticisms of it. In this way, I shall proceed as in a medieval quaestio, with arguments in favour, sed contra and respondeo.

The idea of personalised medicine (PM) has gathered momentum recently, attracting funding and generating hopes as well as scepticism. As PM gives rise to differing interpretations, there have been several attempts to clarify the concept. In an influential paper published in this journal, Schleidgen and colleagues have proposed a precise and narrow definition of PM on the basis of a systematic literature review. Given that their conclusion is at odds with those of other recent attempts to understand PM, we consider (...) whether their systematic review gives them an edge over competing interpretations. We have found some methodological weaknesses and questionable assumptions in Schleidgen and colleagues’ attempt to provide a more specific definition of PM. Our perplexities concern the lack of criteria for assessing the epistemic strength of the definitions that they consider, as well as the logical principles used to extract a more precise definition, the narrowness of the pool from which they have drawn their empirical data, and finally their overlooking the fact that definitions depend on the context of use. We are also worried that their ethical assumption that only patients’ interests are legitimate is too simplistic and drives all other stakeholders’ interests—including those that are justifiable—underground, thus compromising any hope of a transparent and fair negotiation among a plurality of actors and interests. As an alternative to the shortcomings of attempting a semantic disciplining of the concept we propose a pragmatic approach. Rather than considering PM to be a scientific concept in need of precise demarcation, we look at it as an open and negotiable concept used in a variety of contexts including at the level of orienting research goals and policy objectives. We believe that since PM is still more an ideal than an achieved reality, a plurality of visions is to be expected and we need to pay attention to the people, reasons and interests behind these alternative conceptions. In other words, the logic and politics of PM cannot be disentangled and disagreements need to be tackled addressing the normative and strategic conflicts behind them. (shrink)

Richard Shusterman suggested that Maurice Merleau-Ponty neglected “‘lived somaesthetic reflection,’ that is, concrete but representational and reflective body consciousness.” While unsure about this assessment of Merleau-Ponty, lived somaesthetic reflection, or what the late Sam Mallin called “body phenomenology”—understood as a meditation on the body reflecting on both itself and the world—is my starting point. Another is John Dewey’s bodily theory of perception, augmented somewhat by Merleau-Ponty. -/- With these starting points, I spent roughly 20 hours with St. Benedict Restores Life (...) to a Young Monk (c. 1360), a work of tempera and gold leaf on panel, by Giovanni Del Biondo, active in Italy from 1356 to 1398, on display in the Art Gallery of Ontario’s permanent collection. Following Dewey’s suggestion that “[t]he eye ... is only the channel through which a total response takes place,” meaning that motor, emotional, intellectual and non-visual perceptual capacities become active when we encounter paintings, I describe how the work engaged a range of bodily modalities; and how reflecting on these, in turn, supplied phenomenal articulations of life negating, preserving and enhancing forces important in the culture that produced it, and famously discussed by Friedrich Nietzsche. By virtue of the approach adopted, I also demonstrate Dewey’s belief that intimate engagement with art entails a total coordination of one’s capacities around the artwork, while simultaneously reinforcing Merleau-Ponty’s ideas about perception and how we can find phenomenal articulations of concepts such as the Nietzschean ones just mentioned. While focusing on Del Biondo’s painting, my main purpose is to engage in body phenomenology practices, and to show, in the words of Shusterman, how “[w]e might sharpen our appreciation of art through more attention to our somaesthetic feelings involved in perceiving art” and indeed the world. (shrink)

In order to illustrate the difference between sensation and perception, Reid imagines a blind man that by ‘some strange distemper’ has lost all his notions of external objects, but has retained the power of sensation and reasoning. Reid argues that since sensations do not resemble external objects, the blind man could not possibly infer from them any notion of primary qualities. Condillac proposed a similar thought experiment in the Treatise on Sensations. I argue that Condillac can reach a conclusion opposite (...) to that of Reid only by assuming that some particular collections of sensations do indeed resemble the qualities of external objects. Reid had considered a similar case in a manuscript, but he again notices that such complex collections sensations do not resemble the qualities of external objects. (shrink)

The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals. The AOP framework and associated knowledgebases (KBs) have received significant attention and use in the regulatory toxicology community. However, it is increasingly apparent that the potential stakeholder community for the AOP concept and AOP KBs is broader than scientists and regulators directly involved in chemical safety assessment. In this paper we (...) identify and describe those stakeholders who currently—or in the future—could benefit from the application of the AOP framework and knowledge to specific problems. We also summarize the challenges faced in implementing pathway-based approaches such as the AOP framework in biological sciences, and provide a series of recommendations to meet critical needs to ensure further progression of the framework as a useful, sustainable and dependable tool supporting assessments of both human health and the environment. Although the AOP concept has the potential to significantly impact the organization and interpretation of biological information in a variety of disciplines/applications, this promise can only be fully realized through the active engagement of, and input from multiple stakeholders, requiring multi-pronged substantive long-term planning and strategies. (shrink)

There are two intuitions about time. The first is that there's something special about the present that objectively differentiates it from the past and the future. Call this intuition Specialness. The second is that the time at which we happen to live is just one among many other times, all of which are ‘on a par’ when it comes to their forming part of reality. Call this other intuition Egalitarianism. Tradition has it that the so-called ‘A-theories of time’ fare well (...) at addressing the first intuition, but rather badly when it comes to the second. The goal of this article is to offer advice to A-theorists about how to reconcile their view with Egalitarianism. (shrink)

Relativists make room for the possibility of “faultless disagreement” by positing the existence of subjective propositions, i.e. propositions true from some points of view and not others. We discuss whether the adoption of this position with respect to a certain domain of discourse is compatible with a realist attitude towards the matters arising in that domain. At first glance, the combination of relativism and realism leads to an unattractive metaphysical picture on which reality comprises incoherent facts. We will sketch the (...) contours of a realist-relativist position called “subjectivism”, which avoids this result by giving up the assumption that the points of view of different subjects are all metaphysically “on a par”. (shrink)

The article tries to reconstruct the Wirkungsgeschichte of the De pace fidei and it focuses on some fundamental moments of its fate. Nicholas of Cusa was one of the first not just to recognize other religions' value, but also to individuate a source of richness in religious pluralism. His work had fortune since the years after its draft, the 1453, known and quoted by Eimerico da Campo, Giovanni of Segovia, Juan de Torquemada and Pope Pius II. The debate, alive (...) and still open, around the possible influence of the work to Italian humanistic context is reconstructed, in particular about Pico and Ficino. Trusted traces of reception of the work can be individuated in France, in authors like Bodin and Postel. Finally the article is focused on modern fate of the work in Germany: beyond the cultural contest into reception and translation had done, the work analyze the reception by the German philosopher Lessing and on his comparison with Cusanian ideas about the vision of tolerance elaborated by the last one. (shrink)

Giovanni Pico della Mirandola (1463-1494) decided to study all the ancient and medieval schools of philosophy, including the Pre-Socratics, in order to broaden his scope. Pico showed interest in ancient monists. He commented that only Xenophanes’ One is the One simply, while Parmenides’ One is not the absolute One, but the oneness of Being. Melissus’ One is in extreme correspondence to that of Xenophanes. As for Xenophanes, Pico seems to have fallen victim of ancient sources, who referred to Xenophanes (...) and Parmenides as members of the Eleatic “tribe”. In the case of Parmenides Pico draws mainly on the Platonic dialogues Parmenides and Sophist and not on intermediaries such as the Neoplatonists and other commentators. Despite of Pico’s knowledge of Empedocles’ philosophy, it is worth noticing that Pico was also strongly influenced by the medieval kabbalistic literature and the pseudo Empedocles. While Neoplatonists, such as Proclus, commented Empedocles and interpreted him according to the Neoplatonic spectrum, Pico’s appreciation of the philosophy of Empedocles was mediated through Arab and Jewish mysticism. Pico counted among his sources the Pre-Socratics, but the way he read them was not always direct and consistent. He intentionally chose to interpret them through the spectrum of intermediaries such as the ancient Commentators, the Neoplatonists, the Arabs and Jews mystics. (shrink)

Cartesians and Lichtenbergians have diverging views of the deliverances of introspection. According to the Cartesians, a rational subject, competent with the relevant concepts, can come to know that he or she thinks – hence, that he or she exists – on the sole basis of his or her introspective awareness of his or her conscious thinking. According to the Lichtenbergians, this is not possible. This paper offers a defence of the Lichtenbergian position using Peacocke and Campbell's recent exchange on Descartes's (...) cogito as a framework for discussion. A thought-experiment will be presented involving two communities with radically different conceptions of the metaphysics of the self. The purpose of the thought-experiment is to suggest that a substantive metaphysical thesis, whose truth cannot be a priori known, is presupposed by any justified transition from one's introspective awareness of a certain mental activity to the self-ascription of that activity. (shrink)

Assuming a radical stance on embodied cognition, according to which the information ac- quired through basic cognitive processes is not contentful (Hutto and Myin, 2013), and as- suming that perception is a source of rationally grounded knowledge (Pritchard, 2012), a pluralistic account of perceptual knowledge is developed. The paper explains: (i) how the varieties of perceptual knowledge fall under the same broader category; (ii) how they are subject to the same kind of normative constraints; (iii) why there could not be (...) a conflict between the different varieties of perceptual knowledge; and (iv) why the traditional episte- mological inquiry is inclined to overestimate the role of propositional perceptual knowledge. (shrink)

According to Leibniz’s infinite-analysis account of contingency, any derivative truth is contingent if and only if it does not admit of a finite proof. Following a tradition that goes back at least as far as Bertrand Russell, several interpreters have been tempted to explain this biconditional in terms of two other principles: first, that a derivative truth is contingent if and only if it contains infinitely complex concepts and, second, that a derivative truth contains infinitely complex concepts if and only (...) if it does not admit of a finite proof. A consequence of this interpretation is that Leibniz’s infinite-analysis account of contingency falls prey to Robert Adams’s Problem of Lucky Proof. I will argue that this interpretation is mistaken and that, once it is properly understood how the idea of an infinite proof fits into Leibniz’s circle of modal notions, the problem of lucky proof simply disappears. (shrink)

Victor Eremita proposes that the reader understand parts I and II of Either/Or as parties in a dialogue; most readers in fact view II as a devastating reply to I. I suggest that part I be read as a reaction or follow-up to Kierkegaard’s dissertation. Much of part I presents reflective characters who are aware of their freedom but reluctant or unable to adopt the ethical life. The modern Antigone and the Silhouettes are sisters of Alcibiades—failed students of Socrates. I (...) articulate and defend their modes of loving, which are significantly different from Don Giovanni’s and Johannes the Seducer’s purely aesthetic approaches to love. Such feminine love, I argue, dwells in the disputed territory between passion and action, substance and freedom, the aesthetic and the ethical. Antigone’s love is a passion she both suffers and tries to appropriate. The Silhouettes’ devotion to their beloved makes them dependent on him. I defend this dependence even though it is undoubtedly a form of despair. By appealing to Sartre’s account of love, I argue moreover that this love involves a recognition and appraisal of the beloved absent in the love exemplified by Fear and Trembling’s knight of infinite resignation. (shrink)

The background paper provides an introduction to the concept of pandemics and to the ethical and political issues related with pandemic preparedness.

We present an algebraic account of the Tongan kinship terminology (TKT) that provides an insightful journey into the fabric of Tongan culture. We begin with the ethnographic account of a social event. The account provides us with the activities of that day and the centrality of kin relations in the event, but it does not inform us of the conceptual system that the participants bring with them. Rather, it is a slice in time of an ongoing dynamic process that links (...) behavior with a conceptual system of kin relations and vice versa. To understand this interplay, we need an account of the underlying conceptual system that is being activated during the event. Thus, we introduce a formal, algebraically based account of TKT. This account brings to the fore the underlying logic of TKT and allows us to distinguish between features of the kinship system that arise from the logic of TKT as a generative structure and features that must have arisen through cultural intervention. (shrink)

In this paper, I argue that knowledge is dimly luminous. That is: if a person knows that p, she knows how she knows that p. The argument depends on a safety-based account of propositional knowledge, which is salient in Williamson’s critique of the ‘KK’ principle. I combine that account with non-intellectualism about knowledge-how – according to which, if a person knows how to φ, then in nearly all nearby possible worlds in which she φes in the same way as in (...) the actual world, she only φes successfully. Thus, the possession of first-order propositional knowledge implies secondorder practical knowledge, and this can be iterated. Because of the assumed nonintellectualism about know-how, dim luminosity does not imply bright luminosity about knowledge, which is expressed by the traditional KK principle. I conclude by considering some potential counterexamples to the view that knowledge is dimly luminous. (shrink)

It has been observed that, unlike other kinds of singular judgments, mental self-ascriptions are immune to error through misidentification: they may go wrong, but not as a result of mistaking someone else’s mental states for one’s own. Although recent years have witnessed increasing interest in this phenomenon, three basic questions about it remain without a satisfactory answer: what is exactly an error through misidentification? What does immunity to such errors consist in? And what does it take to explain the fact (...) that mental self-ascriptions exhibit this sort of immunity? The aim of this paper is to bring these questions into focus, propose some tentative answers and use them to show that one prominent attempt to explain the immunity to error through misidentification of mental self-ascriptions is unsuccessful. (shrink)

Kilimanjaro is an example of what some philosophers would call a ‘vague object’: it is only roughly 5895 m tall, its weight is not precise and its boundaries are fuzzy because some particles are neither determinately part of it nor determinately not part of it. It has been suggested that this vagueness arises as a result of semantic indecision: it is because we didn’t make up our mind what the expression “Kilimanjaro” applies to that we can truthfully say such things (...) as “It is indeterminate whether this particle is part of Kilimanjaro”. After reviewing some of the limitations of this approach, I will propose an alternative account, based on a new semantic relation—multiple reference—capable of holding in a one-many pattern between a term and several objects in the domain. I will explain how multiple reference works, what differentiates it from plural reference and how it might be used to accommodate at least some aspects of our ordinary discourse about vague objects. (shrink)

While Hume had a favorable opinion of the new commercial society, Reid envisioned a utopian system that would eliminate private property and substitute the profit incentive with a system of state-conferred honors. Reid’s predilection for a centralized command economy cannot be explained by his alleged discovery of market failures, and has to be considered in the context of his moral psychology. Hume tried to explain how the desire for gain that motivates the merchant leads to industry and frugality. These, in (...) their turn, benefit all society. Reid still saw the desire for money as a degenerate form of the desire for power. The contrast between Hume and Reid, however, has not to be taken too far. On some particular matters of economic policy, such as paper credit, Hume and Reid eventually came to similar views. (shrink)

In this article we raise a problem, and we offer two practical contributions to its solution. The problem is that academic communities interested in digital publishing do not have adequate tools to help them in choosing a publishing model that suits their needs. We believe that excessive focus on Open Access (OA) has obscured some important issues; moreover exclusive emphasis on increasing openness has contributed to an agenda and to policies that show clear practical shortcomings. We believe that academic communities (...) have different needs and priorities; therefore there cannot be a ranking of publishing models that fits all and is based on only one criterion or value. We thus believe that two things are needed. First, communities need help in working out what they want from their digital publications. Their needs and desiderata should be made explicit and their relative importance estimated. This exercise leads to the formulation and ordering of their objectives. Second, available publishing models should be assessed on the basis of these objectives, so as to choose one that satisfies them well. Accordingly we have developed a framework that assists communities in going through these two steps. The framework can be used informally, as a guide to the collection and systematic organization of the information needed to make an informed choice of publishing model. In order to do so it maps the values that should be weighed and the technical features that embed them. Building on our framework, we also offer a method to produce ordinal and cardinal scores of publishing models. When these techniques are applied the framework becomes a formal decision–making tool. Finally, the framework stresses that, while the OA movement tackles important issues in digital publishing, it cannot incorporate the whole range of values and interests that are at the core of academic publishing. Therefore the framework suggests a broader agenda that is relevant in making better policy decisions around academic publishing and OA. (shrink)

The paper discusses some of the implications of regulatory innovation in the area of advanced biological therapies and personalised medicine. Benefits, risks and trade-offs are highlighted.

In a recent article on Reid’s theory of single and double vision, James Van Cleve considers an argument against direct realism presented by Hume. Hume argues for the mind-dependent nature of the objects of our perception from the phenomenon of double vision. Reid does not address this particular argument, but Van Cleve considers possible answers Reid might have given to Hume. He finds fault with all these answers. Against Van Cleve, I argue that both appearances in double vision could be (...) considered visible figures of the object, and show how this solution might preserve Reid’s direct realism. However, this solution is not compatible with the single appearance of an object predicted by Reid’s theory of single and double vision. This consequence will appear evident once we consider the critique of Reid’s theory of single and double vision formulated by William Charles Wells (1757-1817). Wells argues that Reid’s theory is either incomplete or incompatible with other claims made by Reid. It is incomplete since it fails to specify the unique direction in which we the object in single vision; if it not incomplete and is compatible with the law of monocular direction given by Reid, then it is incompatible with Reid’s claim that we do not perceive immediately distance by sight. (shrink)

Primeiro apresento as linhas gerais do programa de pesquisa sobre cognição corporificada. Em uma posição central nesse programa, está a tese de que a cognição atravessa cérebro, corpo e mundo – e que, portanto, atividades cognitivas não são eventos exclusivamente intracraniais que ocorrem pela manipulação de representações. Eu apresento a gênese histórica desse programa, a saber, o projeto autopoiético dos chilenos Humberto Maturana e Francisco Varela. Desse projeto, é possível atestar um plano de fundo antirrealista e construtivista, segundo o qual (...) a cognição é uma construção do mundo pelo organismo. Depois, eu apresento o fundamento teórico que recentemente tomou os holofotes do programa, a saber, o enativismo sensório-motor. Esse enativismo manifesta o compromisso com um realismo comedido, segundo o qual há estruturas objetivas a serem exploradas de acordo com a morfologia corpórea do organismo. Assim, observa-se uma tensão epistemológica no cerne do programa. Eu apresento uma possibilidade de resolução dessa tensão pela rejeição de uma das teses centrais do projeto autopoiético – a continuidade forte entre vida e cognição – e por uma melhor interpretação do que significa dizer que a cognição requer que o oragnismo “construa” o seu ambiente. (shrink)

Not unlike many contemporary philosophers, Leibniz admitted the existence of temporary truths, true propositions that have not always been or will not always be true. In contrast with contemporary philosophers, though, Leibniz conceived of truth in terms of analytic containment: on his view, the truth of a predicative sentence consists in the analytic containment of the concept expressed by the predicate in the concept expressed by the subject. Given that analytic relations among concepts are eternal and unchanging, the problem arises (...) of explaining how Leibniz reconciled one commitment with the other: how can truth be temporary, if concept-containment is not? This paper presents a new approach to this problem, based on the idea that a concept can be consistent at one time and inconsistent at another. It is argued that, given a proper understanding of what it is for a concept to be consistent, this idea is not as problematic as it may seem at first, and is in fact implied by Leibniz’s general views about propositions, in conjunction with the thesis that some propositions are only temporarily true. (shrink)

The article presents another of those ingenious mind, rebels to the yoke of religion, typical of the Italian Renaissance. Converted to Calvinism and therefore condemned to death by the Inquisition, Guglielmo Grataroli (1516-1568) became a defender of heterodox doctrine. His translation of a report of the Waldensian massacre in Calabria became part of the history of Protestant martyrs. He was the author of numerous treatises on various subjects, for which he widely used the works of Giovanni Michele Alberto da (...) Carrara, Antoine Mizauld and Gerolamo Cardano. The perfect correspondence of the topics discussed makes it probable that Giordano Bruno knew his writings. In particular, the De mutatione temporum, eiusque signis perpetuis may have inspired the De’ segni de’ tempi, a Bruno’s lost opera. This allows us to conjecture the content of the work with greater reliability. (shrink)

Based on Pritchard's distinction between favoring and discriminating epistemic grounds, and on how those grounds bear on the elimination of skeptical possibilities, I present the dream argument as a moderate skeptical possibility that can be reasonably motivated. In order to block the dream argument skeptical conclusion, I present a version of phenomenological disjunctivism based on Noë's actionist account of perceptual consciousness. This suggests that perceptual knowledge is rationally grounded because it is a form of embodied achievement - what I call (...) embodied rationality -, which offers a way of dissolving the pseudo-problem of epistemic immodesty, namely, the seemingly counterintuitive thesis that one can acquire rationally grounded knowledge that one is not in a radical skeptical scenario. (shrink)

I advance the Radically Enactive Cognition (REC) program by developing Hutto & Satne’s (2015) and Hutto & Myin’s (2017) idea that contentful cognition emerges through sociocultural activities, which require a contentless form of intentionality. Proponents of REC then face a functional challenge: what is the function of higher cognitive skills, given the empirical findings that engaging in higher-cognitive activities is not correlated with cognitive amelioration (Kornblith, 2012)? I answer that functional challenge by arguing that higher cognition is an adaptive tool (...) of the social systems we are embedded in, therefore, it is not necessarily aimed at achieving better cognitive states. In order to do so, I suggest interpreting key insights from autopoietic enactivism through REC lenses. (shrink)