The purpose is to provide researchers with reliable Scientific Research Data from the massive amounts of research data to establish a sustainable Scientific Research environment. Specifically, the present work proposes establishing an Intelligent Recommendation System based on Machine Learning algorithm and SRD. Firstly, the IRS is established over ML technology. Then, based on user Psychology and Collaborative Filtering recommendation algorithm, a hybrid algorithm [namely, Content-Based Recommendation-Collaborative Filtering ] is established to improve the utilization efficiency of SRD and Sustainable Development of (...) SR. Consequently, the present work designs literature and SRD-targeted IRS using the hybrid recommendation under the background of SD. The proposed system’s feasibility is analyzed through experiments. Additionally, the system performance is analyzed and verified from accuracy, diversity, coverage, novelty, and recommendation efficiency. The results show that the hybrid algorithm can make up for the shortcomings of a single algorithm and improve the recommendation efficiency. Experiments show that the accuracy of the proposed CBR-CF algorithm is the highest. In particular, the recommendation accuracy for the single-user system can reach 82–93%, and the recall of all recommended algorithms falls between 60 and 91%. The recall of the hybrid algorithm is higher than that of a single algorithm, and the highest recall is 91%. Meanwhile, the hybrid algorithm has comprehensive coverage, good applicability, and diversity. Therefore, SD-oriented SRD-targeted IRS is of great significance to improve the SRD utilization and the accuracy of IRS, and expand the achievement value of SR. The research content provides a reference for establishing a sustainable SR environment and improving SR efficiency. (shrink)