Charles S. Peirce’s philosophy of signs, generally construed as the foundation of current semiotic theory, offers a theory of general perception with significant implications for the notion of subjectivity in organisms. In this article, we will discuss Peirce’s primary claims in semiotic theory, particularly focusing on their relevance to biosemiotics. We argue that these claims align with certain areas of the philosophy of biology, specifically epistemological and ontological considerations, despite the limited formal interaction between disciplines. This article serves as a (...) general introduction to Peircean biosemiotics as a philosophical perspective on biological subjectivity. (shrink)