In this article, I make a novel argument for scientific antirealism. My argument is as follows: (1) the best human chess players would lose to the best computer chess programs; (2) if the best human chess players would lose to the best computer chess programs, then there is good reason to think that the best human chess players do not understand how to make winning moves; (3) if there is good reason to think that the best human chess players do (...) not understand how to make winning moves, then there is good reason to think that the best human theories about unobservables are wrong; therefore, (4) there is good reason to think that the best human theories about unobservables are wrong. The article is divided into three sections. In the first, I outline the backdrop for my argument. In the second, I explain my argument. In the third, I consider some objections. (shrink)