The eminent French biologist and historian of biology, François Jacob, once notoriously declared “On n’interroge plus la vie dans les laboratoires”: laboratory research no longer inquires into the notion of ‘Life’. Nowadays, as David Hull puts it, “both scientists and philosophers take ontological reduction for granted… Organisms are ‘nothing but’ atoms, and that is that.” In the mid-twentieth century, from the immediate post-war period to the late 1960s, French philosophers of science such as Georges Canguilhem, Raymond Ruyer and Gilbert Simondon (...) returned to Jacob’s statement with an odd kind of pathos: they were determined to reverse course. Not by imposing a different kind of research program in laboratories, but by an unusual combination of historical and philosophical inquiry into the foundations of the life sciences (particularly medicine, physiology and the cluster of activities that were termed ‘biology’ in the early 1800s). Even in as straightforwardly scholarly a work as La formation du concept de réflexe aux XVIIe et XVIIIe siècles (1955), Canguilhem speaks oddly of “defending vitalist biology,” and declares that Life cannot be grasped by logic (or at least, “la vie déconcerte la logique”). Was all this historical and philosophical work merely a reassertion of ‘mysterian’, magical vitalism? In order to answer this question we need to achieve some perspective on Canguilhem’s ‘vitalism’, notably with respect to its philosophical influences such as Kurt Goldstein. (shrink)

This paper offers an intellectual history of the scientific realism debate during the twentieth century. The telling of the tale will explain the philosophical significance and the prospects of the scientific realism debate, through the major turns it went through. The emphasis will be on the relations between empiricism and scientific realism and on the swing from metaphysics-hostile to metaphysics-friendly versions of realism.

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and (...) above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice. Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist. Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current theorizing of vitalism. (shrink)

This chapter offers a narrative of the basic twists and turns of the realism debate after the realist turn. It starts with what preceded and initiated the turn, viz., instrumentalist construals of scientific theories. It then moves on to discuss the basic lines of development of the realist stance to science, focusing on one of its main challenges: the historical challenge.

This essay attempts to distinguish the pressing issues for economists and economic methodologists concerning realism in economics from those issues that are of comparatively slight importance. In particular I shall argue that issues concerning the goals of science are of considerable interest in economics, unlike issues concerning the evidence for claims about unobservables, which have comparatively little relevance. In making this argument, this essay raises doubts about the two programs in contemporary economic methodology that raise the banner of realism. In (...) particular I argue that the banner makes it more difficult to relate the concerns of those who wave it to those of other methodologists. Although this essay argues that many of the debates in this century between scientific realists and their opponents are not relevant to economics, it does not attack scientific realism, and it does not urge economists or economic methodologists to reject it. (shrink)

Hans Hahn's long-neglected philosophy of mathematics is reconstructed here with an eye to his anticipation of the doctrine of logical pluralism. After establishing that Hahn pioneered a post-Tractarian conception of tautologies and attempted to overcome the traditional foundational dispute in mathematics, Hahn's and Carnap's work is briefly compared with Karl Menger's, and several significant agreements or differences between Hahn's and Carnap's work are specified and discussed.

The present paper studies a specific way of addressing the question whether the laws involving the basic constituents of nature are statistical. While most German physicists, above all Planck, treated the issues of determinism and causality within a Kantian framework, the tradition which I call Vienna Indeterminism began from Mach’s reinterpretation of causality as functional dependence. This severed the bond between causality and realism because one could no longer avail oneself of a priori categories as a criterion for empirical reality. (...) Hence, an independent reality criterion had to be sought, a problem which all three physicists to be studied solved in different ways that were mainly conditioned by their different concepts of probability. In order to prevent a dissipation of intuited facts, Mach had to resort to a principle of unique determination as his reality criterion, especially when discussing the Principle of Least Action. Giving theories more independence, Boltzmann understood atomism as property reduction to precisely defined theoretical entities and their interactions. While this served as a relative reality criterion, he also advocated a constructivist one because atomism was already implied by our finitary reasoning power. Finally, Exner contemplated the idea that all apparently deterministic laws are only a macroscopic limit of an irreducible indeterminism, because by adopting the frequency interpretation, observable collectives could be considered as the real basic entities. (shrink)

Based on texts and personal recollections, the paper discusses the origins and roots of Philipp Frank’s philosophy of science as it was developed in Eastern Europe and later institutionalized in the United States. It takes into account the influence of Abel Rey and V. I. Lenin, considering the idea of the “bankruptcy of science.”.

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and (...) above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice (Wolfe and Normandin, eds. 2013). Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist (Gilbert and Sarkar 2000, Moreno and Mossio 2015). Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current (re-)theorizing of vitalism. (shrink)

In biology the term “vitalism” is usually associated with Hans Driesch’s doctrine of the entelechy: entelechies were nonmaterial, bio-specific agents responsible for governing a few peculiar biological phenomena. Since vitalism defined as such violates metaphysical materialism, the received view refutes the doctrine of the entelechy as a metaphysical heresy. But in the early twentieth century, a different, non-metaphysical evaluation of vitalism was endorsed by some biologists and philosophers, which finally led to a logical refutation of the doctrine of the entelechy. (...) In this non-metaphysical evaluation, first, vitalism was not treated as a metaphysical heresy but a legitimate response to the inadequacy of mechanistic explanations in biology. Second, the refutation of vitalism was logically rather than metaphysically supported by contemporary biological knowledge. The entelechy was not a valid concept, because vitalists could neither formulate vital laws, nor offer convincing examples of experimental indeterminism. (shrink)