Proceeding from a philosophical interpretation of negative theology as performatively undermining our seeming understanding of the absolute and thereby evoking a transformative experience, this paper emphasises the philosophical significance of negative theology by linking it to Karl Jaspers’ notion of the universal limit situation of existence. Against this background, an analysis of mystical and psychotic experiences shows how certain similarities between the two can be understood as constituting a particular mental state in which the universal limit situation is experienced personally. (...) Moreover, experiencing the limit situation, be it through this mental state or through certain moods or feelings, can be transformative and may lead to an attitude of groundless trust that acknowledges the incomprehensibility of the human condition. The paper argues that this reading of negative theology provides a better understanding of the parallels between mysticism and psychosis and may be fruitfully applied in therapy. (shrink)