The social sciences often explain behavioral differences by appealing to membership in distinct cultural groups. This work uses the concepts of “cultures” and “cultural groups” like any other demographic category (e.g. “gender”, “socioeconomic status”). I call these joint conceptualizations of “cultures” and “cultural groups” _demographic cultures_. Such demographic cultures have long been subject to scrutiny. Here I isolate and respond to a set of arguments I call _demographic skepticism_. This skeptical position denies that the demographic cultures concept can support metaphysically (...) plausible and empirically principled research. I argue against the skeptic, showing that their position relies on a questionable alignment between the demographic cultures concept and what I call the _folk anthropological model_. While the commitments of that model are problematic—they are not necessary for comparative work in the social sciences. In addition to clarifying skeptical arguments, then, I provide four recommendations for the comparative social scientist that allow them to avoid demographic skepticism. (shrink)