Much of the recent philosophical debate on causation and causal explanation in the biological and biomedical sciences has focused on the notion of mechanism. Mechanisms, their nature and epistemic roles have been tackled by a range of so-called neo-mechanistic theories, and widely discussed. Without denying the merits of this approach, our paper aims to show how lately it has failed to give proper credit to processes, which are central to the field, especially of contemporary molecular biology. Processes can be summed (...) up in the notion of ‘pathway’, which is far from being just equivalent to that of ‘mechanism’ and has a profound epistemological and explanatory relevance. It is argued that an adequate consideration of pathways impels some rethinking of scientific explanation in molecular biology, namely its functional and contextual features. A number of examples are given to suggest that the focus of philosophical attention in this disciplinary field should shift from the notion of mechanism to the notion of pathway. (shrink)

A classic challenge for any theory of physical causation based on conserved quantities and formulated within the framework of special relativity theory, has been to distinguish two regions, that of genuine causal relationships and that of those spurious or noncausal ones. In the causal processes theory defended by P. Dowe, this is done by introducing a criterion based on the possession of a conserved quantity, which would seem to efficiently demarcate between causal processes and causal pseudoprocesses. However, faced with criticism (...) about the inadequacy of his criteria, Dowe has proposed modifying his physical ontology and introducing, along with processes and pseudo-processes, two types of physical gerrymander entities, both temporal and spatial. In this article, we analyze and criticize, from the perspective of ERT, Dowe’s characterization of these quasi-entities and the theoretical need to make a clear-cut distinction between them. This implies a fundamental modification of Dowe's ontology and raises other doubts about its original motivation. (shrink)