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Medical Thinking: A Historical Preface

Princeton Univ Pr (1982)

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  1. Theory of signs and statistical approach to big data in assessing the relevance of clinical biomarkers of inflammation and oxidative stress.Pietro Ghezzi, Kevin Davies, Aidan Delaney & Luciano Floridi - 2018 - Proceedings of the National Academy of Sciences of the United States of America 115 (10):2473-2477.
    Biomarkers are widely used not only as prognostic or diagnostic indicators, or as surrogate markers of disease in clinical trials, but also to formulate theories of pathogenesis. We identify two problems in the use of biomarkers in mechanistic studies. The first problem arises in the case of multifactorial diseases, where different combinations of multiple causes result in patient heterogeneity. The second problem arises when a pathogenic mediator is difficult to measure. This is the case of the oxidative stress (OS) theory (...)
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  • What are chronic diseases?Jonathan Fuller - 2018 - Synthese 195 (7):3197-3220.
    What kind of a thing are chronic diseases? Are they objects, bundles of signs and symptoms, properties, processes, or fictions? Rather than using concept analysis—the standard approach to disease in the philosophy of medicine—to answer this metaphysical question, I use a bottom-up, inductive approach. I argue that chronic diseases are bodily states or properties—often dispositional, but sometimes categorical. I also investigate the nature of related pathological entities: pathogenesis, etiology, and signs and symptoms. Finally, I defend my view against alternate accounts (...)
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  • The (gendered) construction of diagnosis interpretation of medical signs in women patients.Kirsti Malterud - 1999 - Theoretical Medicine and Bioethics 20 (3):275-286.
    Medicine maintains a distinction between the medical symptom -- the patient''ssubjective experience and expression, and the privileged medical sign -- the objective findings observable by the doctor. Although the distinction is not consistently applied, it becomes clearly visible in the undefined, medically unexplained disorders of women patients. Potential impacts of genderized interaction on the interpretation of medical signs are addressed by re-reading the diagnostic process as a matter of social construction, where diagnosis results from human interpretation within a sociopolitical context. (...)
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  • Understanding medical symptoms: a conceptual review and analysis.Kirsti Malterud, Ann Dorrit Guassora, Anette Hauskov Graungaard & Susanne Reventlow - 2015 - Theoretical Medicine and Bioethics 36 (6):411-424.
    The aim of this article is to present a conceptual review and analysis of symptom understanding. Subjective bodily sensations occur abundantly in the normal population and dialogues about symptoms take place in a broad range of contexts, not only in the doctor’s office. Our review of symptom understanding proceeds from an initial subliminal awareness by way of attribution of meaning and subsequent management, with and without professional involvement. We introduce theoretical perspectives from phenomenology, semiotics, social interactionism, and discourse analysis. Drew (...)
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  • Public Health as a Matter of Concern: Victorian England, 1834-1848.Michael Strand - 2019 - Science, Technology, and Human Values 44 (3):399-423.
    Public health is currently evolving, expanding, and reinforcing itself as a governance project in which health authorities’ concerns meet and blend with epidemiology and civil engineering. Rarely, however, are those concerns found worthy of examination, at least not to account for the multiplying involvements of public health, its ability to find political life in things, and its many translations. The shape of public health is dictated as much by its matters of concern as it is by biopolitical and brute matters (...)
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  • What the philosophy of medicine is.Edmund D. Pellegrino - 1998 - Theoretical Medicine and Bioethics 19 (4):315-336.
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  • The tacit–explicit connection: Polanyian integrative philosophy and a neo-polanyian medical epistemology.S. R. Jha - 1998 - Theoretical Medicine and Bioethics 19 (6):547-568.
    The purpose of this paper is to introduce an approach to clinical practice aiming to resolve the dilemma of choosing between a mechanistic and a phenomenological model. The approach is an extension of Polanyi's epistemology. Michael Polanyi, devised an epistemology of science which overcomes the problem of detachment, inherent in the mechanistic approach, and resolves the problem of subjectivity troubling phenomenologists. His epistemology is known as Personal Knowledge. An extension of this epistemology, a Neo-Polanyian proposal, is offered as a more (...)
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  • Medicine and epistemology: Michel Foucault and the liberality of clinical reason.Thomas Osborne - 1992 - History of the Human Sciences 5 (2):63-93.
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