Apart from positive priming effects, masked prime stimuli can impair responses to a subsequent target stimulus which shares response-critical features in contrast to a target assigned to the opposite response. This counterintuitive phenomenon is called inverse priming . Here we examine the generality of this phenomenon beyond priming of motor responses. We used a non-motor cue-priming paradigm to study the underlying mechanism of inverse priming for relevant features masks which include task-relevant stimulus features and for irrelevant masks which omit task-relevant (...) features. We found inverse cue-priming effects with both types of masks. With task-irrelevant masks inverse cue-priming was emphasized in those participants being unable to perceive the prime. The existence of inverse non-motor priming under conditions where simple perceptual interactions between the stimuli are ruled out as the source of inverse priming is at odds with the view that inverse priming reflects motor inhibition. Alternatives are discussed. (shrink)