Background Interventions to improve ethical decision-making are available in nursing education. Evidence of its effectiveness is essential. Objective This review examined the effectiveness of interventions to improve nursing students’ ethical decision-making skills. Methods A structured search was performed in Google Scholar, Web of Science, Science Direct, Pubmed, Scopus, Cochrane Library, Elsevier, CINAHL EBSCO, and ULAKBIM. The Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instruments (JBI-MAStARI) was used to assess the quality of studies. Ethical considerations Ethical approval was not (...) required for this systematic review. Findings The final review was composed of six studies of published between January 2013 and 2023. Nine different teaching methods applied to students. Although the importance of ethical decision-making skills in solving ethical problems that nurses may encounter at any time is known, it is thought that there is a lack of data in the literature in the last 10 years. The last 10 years were chosen as this aims to provide a review based on the most current, relevant and quality information. The review indicated that all of the teaching methods improved ethical decision-making. Conclusion Different teaching methods can be used in the nursing education curriculum to meet the learning needs of nursing students in ethical decision-making. (shrink)