In a recent re-assessment of the medical aspects of the Plague of Athens which is, to date, the most scholarly and comprehensive, Poole and Holladay have emphasized the tendency of many infectious diseases markedly to decline in virulence over decades and centuries and, sometimes, significantly to change their clinical manifestations. In the light of modern medicine they consider four possibilities: The Plague was a disease which still exists today. This they regard as improbable, It still exists in some remote place (...) or places unknown to medical science. This is discussed and dismissed, It became extinct, It was caused by an agent which nowadays causes a significantly different clinical syndrome. They conclude as follows: ‘The truth, we suggest, almost certainly lies in possibility or . But we can see no way of choosing between them. On either view the question: “What was the Athenian Plague?” is in principle unanswerable if the questioner is wanting to attach to the Plagsie the name of some modern disease or diseases’. (shrink)

The most striking advances in the knowledge of human anatomy and physiology that the world had ever known—or was to know until the seventeenth century A.D.—took place in Hellenistic Alexandria. The city was founded in 331 B.C. by Alexander the Great. After the tatter's death in 323 B.C. and the subsequent dissolution of his empire, it became the capital of one of his generals, Ptolemy, son of Lagus, who established the Ptolemaic dynasty there. The first Ptolemy, subsequently named Soter , (...) and his son Ptolemy Philadelphus , became immensely enriched by their exploitation of Egypt and raised the city to a position of great wealth and magnificence. Anxious to enhance both their own reputation and the prestige of the kingdom, they sought to rival the cultural and scientific achievements not only of other Hellenistic rulers but even of Athens herself. Their patronage of the arts and sciences, coupled with their establishment of the Museum , together with the Library, made the city the centre of Hellenistic culture. Philosophers, mathematicians, astronomers, artists, poets and physicians were all encouraged to come and work there. (shrink)