A paramount, yet unresolved issue in personalised medicine is that of automated reasoning with clinical guidelines in multimorbidity settings. This entails enabling machines to use computerised generic clinical guideline recommendations and patient-specific information to yield patient-tailored recommendations where interactions arising due to multimorbidities are resolved. This problem is further complicated by patient management desiderata, in particular the need to account for patient-centric goals as well as preferences of various parties involved. We propose to solve this problem of automated reasoning with (...) interacting guideline recommendations in the context of a given patient by means of computational argumentation. In particular, we advance a structured argumentation formalism ABA+G (short for Assumption-Based Argumentation with Preferences (ABA+) and Goals) for integrating and reasoning with information about recommendations, interactions, patient’s state, preferences and prioritised goals. ABA+G combines assumption-based reasoning with preferences and goal-driven selection among reasoning outcomes. Specifically, we assume defeasible applicability of guideline recommendations with the general goal of patient well-being, resolve interactions (conflicts and otherwise undesirable situations) among recommendations based on the state and preferences of the patient, and employ patient-centered goals to suggest interaction-resolving, goal-importance maximising and preference-adhering recommendations. We use a well-established Transition-based Medical Recommendation model for representing guideline recommendations and identifying interactions thereof, and map the components in question, together with the given patient’s state, prioritised goals, and preferences over actions, to ABA+G for automated reasoning. In this, we follow principles of patient management and establish corresponding theoretical properties as well as illustrate our approach in realistic personalised clinical reasoning scenaria. (shrink)

Answer-set programming (ASP) has emerged as a declarative programming paradigm where problems are encoded as logic programs, such that the so-called answer sets of theses programs represent the solutions of the encoded problem. The efficiency of the latest ASP solvers reached a state that makes them applicable for problems of practical importance. Consequently, problems from many different areas, including diagnosis, data integration, and graph theory, have been successfully tackled via ASP. In this work, we present such ASP-encodings for problems associated (...) to abstract argumentation frameworks (AFs) and generalisations thereof. Our encodings are formulated as fixed queries, such that the input is the only part depending on the actual AF to process. We illustrate the functioning of this approach, which is underlying a new argumentation system called ASPARTIX in detail and show its adequacy in terms of computational complexity. (shrink)

It is often necessary and reasonable to justify preferences before reasoning from them. Moreover, justifying a preference ordering is reduced to justifying the criterion that produces the ordering. This paper builds on the well-known ASPIC+ formalism to develop a model that integrates justifying qualitative preferences with reasoning from the justified preferences. We first introduce a notion of preference criterion in order to model the way in which preferences are justified by an argumentation framework. We also adapt the notion of argumentation (...) theory to build a sequence of argumentation frameworks, in which an argumentation framework justifies preferences that are to underlie the next framework. That is, in our formalism, preferences become not only an input of an argumentation framework, but also an output of it. This kind of input-output process can be applied in the further steps of argumentation. We also explore some interesting properties of our formalism. (shrink)

Over the last decade, several extensions of Dung’s Abstract Argumentation Frameworks (AFs) have been introduced in the literature. Some of these extensions concern the nature of the attack relation, such as the consideration of recursive attacks, whereas others incorporate additional interactions, such as a support relation. Recently, the Attack–Support Argumentation Framework (ASAF) was proposed, which accounts for recursive attacks and supports, attacks to supports and supports to attacks, at any level, where the support relation is interpreted as necessity. Currently, to (...) determine the accepted elements of an ASAF (which may be arguments, attacks, and supports) it is required to translate such an ASAF into a Dung’s AF. In this work, we provide a formal characterization of acceptability semantics directly on the ASAF, without requiring such a translation. We prove that our characterization is sound since it satisfies different results from Dung’s argumentation theory; moreover, we formally show that the approach proposed here for addressing acceptability is equivalent to the preexisting one, in which the ASAF was translated into an AF. Also, we formalize the relationship between the ASAF and other frameworks on which it is inspired: the Argumentation Framework with Recursive Attacks (AFRA) and the Argumentation Framework with Necessities (AFN). (shrink)

Argument evaluation, one of the central problems in argumentation theory, consists in studying what makes an argument a good one. This paper proposes a formal approach to argument evaluation from the perspective of justification logic. We adopt a multi-agent setting, accepting the intuitive idea that arguments are always evaluated by someone. Two general restrictions are imposed on our analysis: non-deductive arguments are left out and the goal of argument evaluation is fixed: supporting a given proposition. Methodologically, our approach uses several (...) existing tools borrowed from justification logic, awareness logic, doxastic logic and logics for belief dependence. We start by introducing a basic logic for argument evaluation, where a list of argumentative and doxastic notions can be expressed. Later on, we discuss how to capture the mentioned form of argument evaluation by defining a preference operator in the object language. The intuitive picture behind this definition is that, when assessing a couple of arguments, the agent puts them to a test consisting of several criteria. As a result of this process, a preference relation among the evaluated arguments is established by the agent. After showing that this operator suffers a special form of logical omniscience, called preferential omniscience, we discuss how to define an explicit version of it, more suitable to deal with non-ideal agents. The present work exploits the formal notion of awareness in order to model several informal phenomena: awareness of sentences, availability of arguments and communication between agents and external sources. We discuss several extensions of the basic logic and offer completeness and decidability results for all of them. (shrink)

In this paper, we introduce the methodology and techniques of meta-argumentation to model argumentation. The methodology of meta-argumentation instantiates Dung’s abstract argumentation theory with an extended argumentation theory, and is thus based on a combination of the methodology of instantiating abstract arguments, and the methodology of extending Dung’s basic argumentation frameworks with other relations among abstract arguments. The technique of meta-argumentation applies Dung’s theory of abstract argumentation to itself, by instantiating Dung’s abstract arguments with meta-arguments using a technique called flattening. (...) We characterize the domain of instantiation using a representation technique based on soundness and completeness. Finally, we distinguish among various instantiations using the technique of specification languages. (shrink)