In the present article, working from within the framework of critical rationalism and focusing mostly on the views developed by some Iranian writers, I argue that the programmes of producing ‘Islamic Science’ and ‘Islamisation of Science/Knowledge’ are doomed to failure. I develop my arguments in three parts. I start by explaining that the advocates of the programmes of producing cIS or IoK subscribe to mistaken images of science that are shaped by either a positivist or outmoded culturalist/interpretivist theories of science. (...) I shall then focus on the similarities and differences of ‘science’ and ‘technology’, arguing that despite close interconnection between the two it is of utmost importance, for analytical purposes, to keep these two socially constructed entities apart. Drawing on the above distinction, I argue that while creating ‘Islamic’ or ‘indigenous’ sciences is impossible, constructing ‘Islamic’ or ‘indigenous’ technologies is, in principle, feasible. Lastly, I turn to some of the... (shrink)