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  1. Are animal models predictive for humans?Niall Shanks, Ray Greek & Jean Greek - 2009 - Philosophy, Ethics, and Humanities in Medicine 4:2.
    It is one of the central aims of the philosophy of science to elucidate the meanings of scientific terms and also to think critically about their application. The focus of this essay is the scientific term predict and whether there is credible evidence that animal models, especially in toxicology and pathophysiology, can be used to predict human outcomes. Whether animals can be used to predict human response to drugs and other chemicals is apparently a contentious issue. However, when one empirically (...)
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  • Is the use of sentient animals in basic research justifiable?Ray Greek & Jean Greek - 2010 - Philosophy, Ethics, and Humanities in Medicine 5:14.
    Animals can be used in many ways in science and scientific research. Given that society values sentient animals and that basic research is not goal oriented, the question is raised.
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  • The institutional review board is an impediment to human research: the result is more animal-based research.Mark J. Rice - 2011 - Philosophy, Ethics, and Humanities in Medicine 6:12.
    Biomedical research today can be generally classified as human-based or nonhuman animal-based, each with separate and distinct review boards that must approve research protocols. Researchers wishing to work with humans or human tissues have become frustrated by the required burdensome approval panel, the Institutional Review Board. However, scientists have found it is much easier to work with the animal-based research review board, the Institutional Animal Care and Use Committee. Consequently, animals are used for investigations even when scientists believe these studies (...)
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